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1. (WO2009129335) SELECTIVE INHIBITORS OF HISTONE DEACETYLASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/129335    International Application No.:    PCT/US2009/040709
Publication Date: 22.10.2009 International Filing Date: 15.04.2009
IPC:
C07D 235/06 (2006.01), C07D 235/08 (2006.01), C07D 235/10 (2006.01), C07D 235/12 (2006.01), C07D 235/14 (2006.01)
Applicants: PHARMACYCLICS, INC. [US/US]; 995 East Arques Avenue Sunnyvale, CA 94085 (US) (For All Designated States Except US).
VERNER, Erik [US/US]; (US) (For US Only).
BALASUBRAMANIAN, Sriram [US/US]; (US) (For US Only).
BUGGY, Joseph, J. [US/US]; (US) (For US Only)
Inventors: VERNER, Erik; (US).
BALASUBRAMANIAN, Sriram; (US).
BUGGY, Joseph, J.; (US)
Agent: HOSTETLER, Michael, J.; (US)
Priority Data:
61/045,198 15.04.2008 US
Title (EN) SELECTIVE INHIBITORS OF HISTONE DEACETYLASE
(FR) INHIBITEURS SÉLECTIFS DE L'HISTONE DÉSACÉTYLASE
Abstract: front page image
(EN)Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the acitivy of histone deacetylase 8 (HDAC8). Also described herein are methods of using such HDAC8 inhibitors, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of HDAC8 activity.
(FR)Cette invention concerne des composés et des compositions pharmaceutiques les contenant, qui inhibent l'activité histone désacétylase 8 (HDAC8). Des procédés d'utilisation de ces inhibiteurs de HDAC8, seuls ou en combinaison avec d'autres composés, sont également décrits pour traiter des maladies ou des affections susceptibles de bénéficier d'une inhibition de l'activité HDAC8.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)