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Machine translation
1. (WO2009129163) BIOLOGICAL MARKERS AND RESPONSE TO TREATMENT FOR PAIN, INFLAMMATION, NEURONAL OR VASCULAR INJURY AND METHODS OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/129163    International Application No.:    PCT/US2009/040316
Publication Date: 22.10.2009 International Filing Date: 13.04.2009
IPC:
A61K 33/06 (2006.01), A61K 47/34 (2006.01), A61P 29/00 (2006.01), A61P 25/28 (2006.01), A61P 9/00 (2006.01)
Applicants: MEDTRONIC, INC. [US/US]; 710 Medtronic Parkway MS LC 340 Minneapolis, MN 55432 (US) (For All Designated States Except US).
WARSAW ORTHOPEDIC, INC. [US/US]; 2500 Silveus Crossing Warsaw, IN 46581 (US) (For All Designated States Except US).
ROY, Josee [US/US]; (US) (For US Only).
KIMBLE, Toya, D. [US/US]; (US) (For US Only)
Inventors: ROY, Josee; (US).
KIMBLE, Toya, D.; (US)
Agent: PATEL, Samir, R.; 710 Medtronic Parkway Ms LC340 Minneapolis, MN 55432 (US)
Priority Data:
12/105,666 18.04.2008 US
Title (EN) BIOLOGICAL MARKERS AND RESPONSE TO TREATMENT FOR PAIN, INFLAMMATION, NEURONAL OR VASCULAR INJURY AND METHODS OF USE
(FR) MARQUEURS BIOLOGIQUES, RÉPONSE AU TRAITEMENT CONTRE LA DOULEUR, L’INFLAMMATION ET LES LÉSIONS NEURONALES OU VASCULAIRES, ET PROCÉDÉS D’UTILISATION AFFÉRENTS
Abstract: front page image
(EN)The invention provides methods and kits for treatment of pain, inflammation, neuronal or vascular injury and the use of biomarkers for the assessment of the biological activity or disease state. In one embodiment, the kit comprises a biomembrane sealing agent, such as PEG, a bioactive agent, such as a magnesium compound, and an assay for measuring a biomarker. The biomarker is measured pre-, mid- and post-treatment, and results of the measurements are compared to evaluate the treatment, treatment regimen and outcomes.
(FR)L’invention concerne des procédés et des kits destinés au traitement de la douleur, de l’inflammation, et de lésions neuronales ou vasculaires. L’invention porte également sur l’utilisation de biomarqueurs dans l’évaluation d’une activité biologique ou d’un état d’une maladie. Dans un mode de réalisation, ledit kit comprend un agent de scellement de biomembrane, tel que du PEG, un agent bioactif, tel qu’un composé de magnésium, et un test permettant de mesurer un biomarqueur. Ledit biomarqueur est mesuré avant, au milieu et après le traitement, et les résultats des mesures sont comparés pour évaluer le traitement, le régime de traitement et ses résultats.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)