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1. (WO2009128360) THERAPEUTIC AGENT FOR DIABETES
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2009/128360 International Application No.: PCT/JP2009/057089
Publication Date: 22.10.2009 International Filing Date: 07.04.2009
IPC:
A61K 31/519 (2006.01) ,A61K 31/155 (2006.01) ,A61K 31/4439 (2006.01) ,A61K 38/28 (2006.01) ,A61K 45/00 (2006.01) ,A61P 3/10 (2006.01) ,A61P 5/50 (2006.01) ,A61P 43/00 (2006.01)
Applicants: KISHINO, Michiko[JP/JP]; JP (UsOnly)
SUGARU, Eiji[JP/JP]; JP (UsOnly)
Dainippon Sumitomo Pharma Co., Ltd.[JP/JP]; 6-8, Dosho-machi 2-chome, Chuo-ku, Osaka-shi, Osaka 5418524, JP (AllExceptUS)
Inventors: KISHINO, Michiko; JP
SUGARU, Eiji; JP
Agent: ISOBE, Yutaka; Intellectual Property, Dainippon Sumitomo Pharma Co., Ltd. 33-94, Enoki-cho, Suita-shi Osaka 5640053, JP
Priority Data:
2008-10849918.04.2008JP
Title (EN) THERAPEUTIC AGENT FOR DIABETES
(FR) AGENT THÉRAPEUTIQUE POUR LE DIABÈTE
(JA) 糖尿病治療剤
Abstract: front page image
(EN) Disclosed is a hypoglycemic agent useful for the treatment of diabetes or the like. The hypoglycemic agent comprises a combination of 6-[(3R)-3-aminopiperidin-1-yl]-5-(2-chloro-5- fluorobenzyl)-1,3-dimethyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione which is a pyrrolopyrimidinedione derivative having an inhibitory activity on dipeptidyl peptidase IV (DPP-IV) or a pharmaceutical acceptable salt thereof and a therapeutic agent for diabetes.
(FR) L'invention porte sur un agent hypoglycémique utile pour le traitement du diabète ou similaire. L'agent hypoglycémique comprend une combinaison de 6-[(3R)-3-aminopipéridin-1-yl]-5-(2-chloro-5-fluorobenzyl)-1,3-diméthyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione qui est un dérivé de la pyrrolopyrimidinedione ayant une activité inhibitrice sur la dipeptidyl peptidase IV (DPP-IV) ou d'un sel pharmaceutiquement acceptable de celle-ci, et d'un agent thérapeutique pour le diabète.
(JA) ジペプチジルペプチダーゼIV(DPP-IV)阻害作用を有するピロロピリミジンジオン誘導体、6-[(3R)-3-アミノピペリジン-1-イル]-5-(2-クロロ-5-フルオロベンジル)-1,3-ジメチル-1H-ピロロ[3,2-d]ピリミジン-2,4(3H,5H)-ジオンまたはその薬学的に許容される塩と、糖尿病治療薬との組み合わせによる、糖尿病等の治療に有用な血糖低下剤を提供する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)