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1. (WO2009127666) VACCINATION COMPOSITIONS OR COMBINATIONS AGAINST CANCER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/127666    International Application No.:    PCT/EP2009/054479
Publication Date: 22.10.2009 International Filing Date: 15.04.2009
IPC:
A61K 39/00 (2006.01), A61K 39/39 (2006.01)
Applicants: GLAXOSMITHKLINE BIOLOGICALS S.A. [BE/BE]; Rue de l'Institut 89 B-1330 Rixensart (BE) (For All Designated States Except US).
BRICHARD, Vincent [BE/BE]; (BE) (For US Only).
GERARD, Catherine, Marie, Ghislaine [BE/BE]; (BE) (For US Only).
LOUAHED, Jamila [BE/BE]; (BE) (For US Only).
VOSS, Gerald, Hermann [DE/BE]; (BE) (For US Only)
Inventors: BRICHARD, Vincent; (BE).
GERARD, Catherine, Marie, Ghislaine; (BE).
LOUAHED, Jamila; (BE).
VOSS, Gerald, Hermann; (BE)
Agent: LOVATT, Victoria, Jayne; GlaxoSmithKline Corporate Intellectual Property CN925.1 980 Great West Road Brentford Middlesex TW8 9GS (GB)
Priority Data:
61/045,090 15.04.2008 US
Title (EN) VACCINATION COMPOSITIONS OR COMBINATIONS AGAINST CANCER
(FR) PROCÉDÉ ET COMPOSITIONS
Abstract: front page image
(EN)Vaccine compositions and methods for their use in the stimulation of immune responses in mammals, including humans, are provided. Also provided are methods for the prevention and treatment of cancer. These relate to breaking immune tolerance to selfantigens, inducing CD4+ and CD8+ T-cell responses, and inducing antibody responses in subjects without recourse to complex prime-boost schedules.
(FR)L'invention porte sur des compositions de vaccin et sur des procédés pour leur utilisation dans la stimulation de réponses immunitaires chez les mammifères, comprenant les êtres humains. L'invention porte également sur des procédés pour la prévention et le traitement du cancer. Ceux-ci portent sur une rupture de tolérance immunitaire à des auto-antigènes, induisant des réponses de lymphocytes T CD4+ et CD8+, et induisant des réponses d'anticorps dans des sujets sans recourir à des programmes complexes de primo-vaccination/rappel.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)