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1. (WO2009126675) 2-SULFONYLAMINO-4-HETEROARYL BUTYRAMIDE ANTAGONISTS OF CCR10
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/126675    International Application No.:    PCT/US2009/039850
Publication Date: 15.10.2009 International Filing Date: 08.04.2009
IPC:
C07D 207/34 (2006.01), C07D 211/16 (2006.01), C07D 403/12 (2006.01), C07D 513/04 (2006.01), A61K 31/439 (2006.01), A61P 25/28 (2006.01)
Applicants: BOEHRINGER INGELHEIM INTERNATIONAL GMBH [DE/DE]; Boehringer Ingelheim International Gmbh Binger Strasse 173 55216 Ingelheim (DE) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG [DE/DE]; Boehringer Ingelheim Pharma Gmbh & Co. Kg Binger Strasse 173 55216 Ingelheim (DE) (DE only).
ABEYWARDANE, Asitha [LK/US]; (US) (For US Only).
COGAN, Derek [US/US]; (US) (For US Only).
CHOI, Younggi [KR/US]; (US) (For US Only).
GAO, Donghong A. [CN/US]; (US) (For US Only).
GOLDBERG, Daniel R. [US/US]; (US) (For US Only).
HEIM-RIETHER, Alexander [DE/US]; (US) (For US Only).
MILLER, Craig Andrew [CA/US]; (US) (For US Only).
RAMSDEN, Philip Dean [CA/US]; (US) (For US Only).
SMITH KEENAN, Lana Louise [CA/US]; (US) (For US Only).
SNOW, Roger John [US/US]; (US) (For US Only).
YU, Yang [CN/US]; (US) (For US Only)
Inventors: ABEYWARDANE, Asitha; (US).
COGAN, Derek; (US).
CHOI, Younggi; (US).
GAO, Donghong A.; (US).
GOLDBERG, Daniel R.; (US).
HEIM-RIETHER, Alexander; (US).
MILLER, Craig Andrew; (US).
RAMSDEN, Philip Dean; (US).
SMITH KEENAN, Lana Louise; (US).
SNOW, Roger John; (US).
YU, Yang; (US)
Agent: MORRIS, Michael P.; (US).
DEVLIN, Mary-ellen M.; (US).
STEMPEL, Alan R.; (US).
BOTTINO, Anthony P.; (US).
WITKOWSKI, Timothy X.; (US).
DATLOW, Philip I.; (US).
PETKA, Wendy; (US).
WITTMAYER, Paula K.; (US).
DOW, David A.; (US).
LEBEL, Edouard G.; (US).
KERSHNER, David L.; (US)
Priority Data:
61/043,416 09.04.2008 US
Title (EN) 2-SULFONYLAMINO-4-HETEROARYL BUTYRAMIDE ANTAGONISTS OF CCR10
(FR) ANTAGONISTES DE 2-SULFONYLAMINO-4-HÉTÉROARYL BUTYRAMIDE DE CCR10
Abstract: front page image
(EN)This invention relates to a compound of formula (I) and the pharmaceutically acceptable salts thereof wherein R1, R2, R4. Ar and Het are as defined herein. The invention also relates to methods of using the compound of formula (I) to treat a diseases and disorders that are mediated or sustained through the activity of CCR10.
(FR)Cette invention porte sur un composé de formule (I) et sur les sels pharmaceutiquement acceptables de celui-ci, formule dans laquelle R1, R2, R4, Ar et Het sont tels que définis présentement. L'invention porte également sur des procédés d'utilisation du composé de formule (I) pour traiter des maladies et des troubles qui sont à médiation ou entretenus par l'activité de CCR10.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)