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1. (WO2009125902) ADENO ASSOCIATED VIRUS SEROTYPE FIVE VECTOR FOR TARGETED GENE DELIVERY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/125902    International Application No.:    PCT/KR2008/004476
Publication Date: 15.10.2009 International Filing Date: 01.08.2008
IPC:
C12N 15/66 (2006.01)
Applicants: FOUNDATION FOR INDUSTRY COOPERATION, UNIVERSITY OF ULSAN [KR/KR]; San 29, Mugar 2-dong, Nam-gu, Ulsan 680-749 (KR) (For All Designated States Except US).
INDUSTRY - ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY [KR/KR]; 126, Jukjeon-dong, Suji-gu, Yongin-si, Gyeonggi-do 448-701 (KR) (For All Designated States Except US).
LEE, Heui Ran [KR/KR]; (KR) (For US Only).
CHOI, Han Seok [KR/KR]; (KR) (For US Only).
LEE, Han Sam [KR/KR]; (KR) (For US Only).
KIM, Jee Yeon [KR/KR]; (KR) (For US Only).
SHIN, Oh Kyu [KR/KR]; (KR) (For US Only).
LEE, Won Il [KR/KR]; (KR) (For US Only).
JUNG, Sun JOO [KR/KR]; (KR) (For US Only).
PARK, Kee Rang [KR/KR]; (KR) (For US Only)
Inventors: LEE, Heui Ran; (KR).
CHOI, Han Seok; (KR).
LEE, Han Sam; (KR).
KIM, Jee Yeon; (KR).
SHIN, Oh Kyu; (KR).
LEE, Won Il; (KR).
JUNG, Sun JOO; (KR).
PARK, Kee Rang; (KR)
Agent: KIM, Soon-Woong; 209 KICOX Venture Center, 188-5, Guro-dong, Guro-gu, Seoul 152-050 (KR)
Priority Data:
10-2008-0032245 07.04.2008 KR
Title (EN) ADENO ASSOCIATED VIRUS SEROTYPE FIVE VECTOR FOR TARGETED GENE DELIVERY
(FR) VECTEUR À BASE D'UN AAV (ADENO-ASSOCIATED VIRUS) SÉROTYPE 5 POUR LA DÉLIVRANCE CIBLÉE D'UN GÈNE
Abstract: front page image
(EN)Disclosed herein is the use as a gene carrier of adeno-associated virus serotype 5 having high safety, among adeno-associated virus serotypes. Specifically, disclosed are a targetable, adeno- associated virus serotype 5-derived recombinant virus vector, prepared by inserting a targeting motif peptide, specifically recognizing a target molecule, into the internal amino acid residue of a capsid protein, and a method of delivering a gene in a target cell-specific manner using the vector.
(FR)Cette invention concerne l'utilisation à titre de vecteur génique d'un AAV (adeno-associated virus) sérotype 5 d'une sécurité élevée, parmi les sérotypes AAV. Plus spécifiquement, cette invention décrit un vecteur viral recombiné, pouvant être ciblé, dérivé d'un AAV sérotype 5, préparé par insertion d'un peptide à motif de ciblage, reconnaissant spécifiquement une molécule cible, dans le résidu acide aminé interne d'une protéine de capside, et un procédé de délivrance d'un gène de manière spécifique de cellule cible au moyen dudit vecteur.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)