WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2009125870) PYRIMIDINE, PYRIDINE AND TRIAZINE DERIVATIVES AS MAXI-K CHANNEL OPENERS.
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2009/125870 International Application No.: PCT/JP2009/057541
Publication Date: 15.10.2009 International Filing Date: 08.04.2009
IPC:
C07D 239/47 (2006.01) ,C07D 213/64 (2006.01) ,C07D 239/34 (2006.01) ,C07D 239/42 (2006.01) ,C07D 251/30 (2006.01) ,A61K 31/505 (2006.01) ,A61K 31/44 (2006.01) ,A61K 31/53 (2006.01) ,C07D 401/04 (2006.01) ,C07D 409/14 (2006.01) ,C07D 403/04 (2006.01) ,A61K 31/506 (2006.01) ,A61K 31/4427 (2006.01) ,A61P 13/10 (2006.01) ,A61P 11/06 (2006.01) ,A61P 9/10 (2006.01)
Applicants: TSUZUKI, Yasuyuki; null (UsOnly)
HIRAI, Miki; null (UsOnly)
MITSUBISHI TANABE PHARMA CORPORATION[JP/JP]; 2-6-18, Kitahama, Chuo-ku, Osaka-shi, Osaka 5418505, JP (AllExceptUS)
Inventors: TSUZUKI, Yasuyuki; null
HIRAI, Miki; null
Agent: TSUKUNI, Hajime; SVAX TS Bldg. 22-12, Toranomon 1-chome Minato-ku, Tokyo 1050001, JP
Priority Data:
2008-10107809.04.2008JP
2008-20337806.08.2008JP
Title (EN) PYRIMIDINE, PYRIDINE AND TRIAZINE DERIVATIVES AS MAXI-K CHANNEL OPENERS.
(FR) DÉRIVÉS DE PYRIMIDINE, PYRIDINE ET TRIAZINE EN TANT QU’OUVREURS DE CANAUX MAXI-K
Abstract: front page image
(EN) A compound of formula (A); wherein ring A is an aromatic ring or a heteroaromatic ring; R1 is independently halogen, cyano, etc., each of X1, X2 and X3 is CR2 or nitrogen, R2 is independently hydrogen, etc., n is 0, 1, 2, 3 or 4; -D-Y is -O-CH2COOH, etc, and G is a substituted amino, a substituted heterocyclic group, etc, or a pharmaceutical acceptable salt thereof, has activities of opening BK channels.
(FR) La présente invention concerne un composé de formule A : (A) dans laquelle le cycle A est un cycle aromatique ou un cycle hétéroaromatique; R1 est indépendamment un halogène, un cyano, etc., chacun de X1, X2 et X3 est CR2 ou un azote, R2 est indépendamment un hydrogène, etc., n est 0, 1, 2, 3 ou 4; -D-Y est -O-CH2COOH, etc., et G est un amino substitué, un groupe hétérocyclique substitué, etc., ou un sel pharmaceutiquement acceptable de celui-ci, qui a des activités d’ouverture de canaux BK.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)