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1. (WO2009125394) ANTI HUMAN IMMUNODEFICIENCY ANTIBODIES AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/125394    International Application No.:    PCT/IL2009/000379
Publication Date: 15.10.2009 International Filing Date: 05.04.2009
IPC:
A61K 39/395 (2006.01), A61K 47/48 (2006.01), A61P 31/18 (2006.01), C07K 16/10 (2006.01), C07K 16/28 (2006.01)
Applicants: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. [IL/IL]; Senate House Technion City 32000 Haifa (IL) (For All Designated States Except US).
REITER, Yoram [IL/IL]; (IL) (For US Only).
HAUS-COHEN, Maya [IL/IL]; (IL) (For US Only)
Inventors: REITER, Yoram; (IL).
HAUS-COHEN, Maya; (IL)
Agent: G.E EHRLICH (1995) LTD.; 11 Menachem Begin Street 52521 Ramat Gan (IL)
Priority Data:
61/071,043 09.04.2008 US
Title (EN) ANTI HUMAN IMMUNODEFICIENCY ANTIBODIES AND USES THEREOF
(FR) ANTICORPS ANTI-IMMUNODÉFICIENCE HUMAINE ET LEURS UTILISATIONS
Abstract: front page image
(EN)Provided are antibodies comprising an antigen recognition domain capable of binding an MHC molecule being complexed with a human immunodeficiency virus (HIV) peptide, wherein the antibody does not bind the MHC molecule in an absence of the complexed peptide, and wherein the antibody does not bind the peptide in an absence of the MHC molecule. Also provided are methods of using same for diagnosing HIV infection and treating AIDS.
(FR)L'invention porte sur des anticorps comprenant un domaine de reconnaissance d'antigène capable de se lier à une molécule MHC qui est complexée à un peptide du virus de l'immunodéficience humaine (VIH), l'anticorps ne se liant pas à la molécule MHC en l'absence du peptide complexé, et l'anticorps ne se liant pas au peptide en l'absence de la molécule MHC. L'invention porte également sur des procédés d'utilisation de ces anticorps pour diagnostiquer une infection par le VIH et traiter le SIDA.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)