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1. (WO2009124777) CIS-ACTING DIVERSIFICATION ACTIVATOR AND METHOD FOR SELECTIVE DIVERSIFICATION OF NUCLEIC ACIDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/124777    International Application No.:    PCT/EP2009/002680
Publication Date: 15.10.2009 International Filing Date: 09.04.2009
IPC:
C12N 15/00 (2006.01), C12N 15/01 (2006.01), C12N 5/06 (2006.01)
Applicants: HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) [DE/DE]; Ingolstädter Landstrasse 1, 85764 Neuherberg (DE) (For All Designated States Except US).
BUERSTEDDE, Jean-Marie [DE/DE]; (DE) (For US Only).
CALDWELL, Randolph, B. [US/DE]; (DE) (For US Only).
SCHÖTZ, Ulrike [DE/DE]; (DE) (For US Only)
Inventors: BUERSTEDDE, Jean-Marie; (DE).
CALDWELL, Randolph, B.; (DE).
SCHÖTZ, Ulrike; (DE)
Agent: BEZZUBOVA, Olga; Uexküll & Stolberg Beselerstraße 4 22607 Hamburg (DE)
Priority Data:
08007120.2 10.04.2008 EP
Title (EN) CIS-ACTING DIVERSIFICATION ACTIVATOR AND METHOD FOR SELECTIVE DIVERSIFICATION OF NUCLEIC ACIDS
(FR) ACTIVATEUR DE DIVERSIFICATION AGISSANT EN CIS ET PROCÉDÉ DE DIVERSIFICATION SÉLECTIVE D'ACIDES NUCLÉIQUES
Abstract: front page image
(EN)The invention relates to identification of a cis-acting diversification activator (DIVAC) that is necessary and sufficient for the activation of diversification in transcription units linked thereto. The invention provides a method for diversification of a target nucleic acid comprising introducing a genetic construct comprising the diversification activator into a recipient cell, wherein the diversification activator is linked to the target nucleic acid.
(FR)L'invention porte sur l'identification d'un activateur de diversification agissant en cis (DIVAC) qui est nécessaire et suffisant pour l'activation d'une diversification dans des unités de transcription liées à celui-ci. L'invention porte sur un procédé de diversification d'un acide nucléique cible comprenant l'introduction d'un produit de construction génétique comprenant l'activateur de diversification dans une cellule receveuse, l'activateur de diversification étant lié à l'acide nucléique cible.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)