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1. (WO2009124226) GELSOLIN USES IN NEUROLOGICAL DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/124226    International Application No.:    PCT/US2009/039382
Publication Date: 08.10.2009 International Filing Date: 03.04.2009
IPC:
A01N 37/18 (2006.01)
Applicants: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA [US/US]; 3160 Chestnut Street Suite 200 Philadelphia, PA 19104-6283 (US) (For All Designated States Except US).
BUCKI, Robert [PL/US]; (US) (For US Only).
JANMEY, Paul [US/US]; (US) (For US Only)
Inventors: BUCKI, Robert; (US).
JANMEY, Paul; (US)
Agent: COHEN, Mark, S.; (US)
Priority Data:
61/064,935 03.04.2008 US
Title (EN) GELSOLIN USES IN NEUROLOGICAL DISORDERS
(FR) UTILISATIONS DE GELSOLINE DANS DES TROUBLES NEUROLOGIQUES
Abstract: front page image
(EN)This invention relates to methods of diagnosis, prognosis, and treatment of a neurological disorder. Specifically, the invention is directed to methods of diagnosis, prognosis, and treatment of a neurological disorder based on measuring changes in the level of gelsolin in cerebrospinal fluid. The invention is also directed to a method for treating, inhibiting, or suppressing a bacterial lipoteichoic acid (LTA)-induced pathogenesis in a subject by contacting the subject with a therapeutically effective amount of gelsolin.
(FR)L’invention concerne des procédés de diagnostic, de pronostic et traitement d’un trouble neurologique. Spécifiquement, l’invention concerne des procédés de diagnostic, de pronostic et traitement d’un trouble neurologique basés sur la mesure du changement du niveau de gelsoline dans le fluide cérébrospinal. L’invention concerne également un procédé de traitement, d’inhibition ou de suppression d’une pathogenèse induite par acide lipotéichoïque bactérien (LTA) chez un sujet par mise en contact du sujet avec une quantité thérapeutiquement efficace de gelsoline.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)