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1. WO2009121483 - HIGHLY BRIDGED PEPTIDES FROM ACTINOMADURA NAMIBIENSIS

Publication Number WO/2009/121483
Publication Date 08.10.2009
International Application No. PCT/EP2009/001982
International Filing Date 18.03.2009
Chapter 2 Demand Filed 20.01.2010
IPC
C07K 14/36 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195from bacteria
36from Actinomyces; from Streptomyces (G)
C07K 7/08 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
08having 12 to 20 amino acids
A61K 38/10 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
10Peptides having 12 to 20 amino acids
A61P 31/04 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04Antibacterial agents
A61P 31/12 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
C12P 21/02 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21Preparation of peptides or proteins
02having a known sequence of two or more amino acids, e.g. glutathione
CPC
A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
A61P 31/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04Antibacterial agents
A61P 31/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
C07K 14/36
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195from bacteria
36from Actinomyces; from Streptomyces (G)
C07K 7/08
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
08having 12 to 20 amino acids
Applicants
  • SANOFI-AVENTIS [FR]/[FR] (AllExceptUS)
  • BROENSTRUP, Mark [DE]/[DE] (UsOnly)
  • GUEHRING, Hans [DE]/[DE] (UsOnly)
  • HOFFMANN, Holger [DE]/[DE] (UsOnly)
  • WINK, Joachim [DE]/[DE] (UsOnly)
  • SUESSMUTH, Roderich [DE]/[DE] (UsOnly)
  • SCHMIEDERER, Timo [DE]/[DE] (UsOnly)
Inventors
  • BROENSTRUP, Mark
  • GUEHRING, Hans
  • HOFFMANN, Holger
  • WINK, Joachim
  • SUESSMUTH, Roderich
  • SCHMIEDERER, Timo
Agents
  • SIEBER, Frank
Priority Data
08290324.602.04.2008EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) HIGHLY BRIDGED PEPTIDES FROM ACTINOMADURA NAMIBIENSIS
(FR) PEPTIDES HAUTEMENT PONTÉS PROVENANT D'ACTINOMADURA NAMIBIENSIS
Abstract
(EN)
The invention refers to so-called Labyrinthopeptin derivatives of the formula (I) wherein {A}, {B}, {C}, R1-R6, m and n are as defined herein, obtainable from microorganism strain Actinomadura namibiensis (DSM 6313), its use for the treatment of bacterial infections, viral infections and/or pain, a pharmaceutical composition comprising it, prepro-Labyrinthopeptin, pro-Labyrinthopeptin, and DNA coding for prepro-Labyrinthopeptin and pro-Labyrinthopeptin.
(FR)
L'invention porte sur des dérivés dits de Labyrinthopeptine représentés par la formule (I) dans laquelle {A}, {B}, {C}, R1-R6, m et n sont tels que définis présentement, pouvant être obtenus à partir de la souche de micro-organisme Actinomadura namibiensis (DSM 6313), sur leur utilisation pour le traitement d'infections bactériennes, d'infections virales et/ou de la douleur, sur une composition pharmaceutique les comprenant, sur une prépro-Labyrinthopeptine, sur une pro-Labyrinthopeptine et sur un ADN codant pour la prépro-Labyrinthopeptine et la pro-Labyrinthopeptine.
Related patent documents
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