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1. (WO2009121066) PRODUCING DICARBOXYLIC ACIDS USING POLYKETIDE SYNTHASES

Pub. No.:    WO/2009/121066    International Application No.:    PCT/US2009/038831
Publication Date: Oct 1, 2009 International Filing Date: Mar 30, 2009
IPC: C12N 9/10
C12N 15/74
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
KATZ, Leonard
FORTMAN, Jeffrey, L.
KEASLING, Jay, D.
Inventors: KATZ, Leonard
FORTMAN, Jeffrey, L.
KEASLING, Jay, D.
Title: PRODUCING DICARBOXYLIC ACIDS USING POLYKETIDE SYNTHASES
Abstract:
The present invention provides for a polyketide synthase (PKS) capable of synthesizing a dicarboxylic acid (diacid). Such diacids include diketide-diacids and triketide-diacids. The invention includes recombinant nucleic acid encoding the PKS, and host cells comprising the PKS. The invention also includes methods for producing the diacids.