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Pub. No.:    WO/2009/120927    International Application No.:    PCT/US2009/038509
Publication Date: 01.10.2009 International Filing Date: 27.03.2009
A61K 39/395 (2006.01)
Applicants: GLAXOSMITHKLINE LLC [US/US]; One Franklin Plaza 200 North 16th Street Philadelphia, PA 19102 (US) (For All Designated States Except US).
HARGREAVE, Fredrick, E. [CA/CA]; (CA) (For US Only).
VENTRESCA, Giampietro [IT/GB]; (GB) (For US Only)
Inventors: HARGREAVE, Fredrick, E.; (CA).
VENTRESCA, Giampietro; (GB)
Agent: LOCKENOUR, Andrea, V.; GlaxoSmithKline Corporate Intellectual Property, UW2220 709 Swedeland Road, P.o. Box 1539 King of Prussia, PA 19406-0939 (US)
Priority Data:
61/040,363 28.03.2008 US
Abstract: front page image
(EN)The present invention relates generally to the methods for the treatment and diagnosis of conditions mediated by IL-5 and excess eosinophil production, and more specifically to mAbs, Fabs, chimeric and humanized antibodies. More particularly, the present invention relates generally to the treatment of eosinophilic bronchitis with an anti- IL-5 antibody or fragment thereof.
(FR)La présente invention concerne généralement des procédés pour le traitement et le diagnostic de pathologies médiées par IL-5 et une production excessive d’éosinophiles, et plus spécifiquement des anticorps mAb, Fab, chimères et humanisés. Plus particulièrement, la présente invention concerne généralement le traitement de la bronchite éosinophilique avec un anticorps anti-IL-5 ou un fragment de celui-ci.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)