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1. (WO2009120700) INHIBITION OF DCPS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/120700    International Application No.:    PCT/US2009/038108
Publication Date: 01.10.2009 International Filing Date: 24.03.2009
A61K 31/517 (2006.01)
Applicants: FAMILIES OF SPINAL MUSCULAR ATROPHY [US/US]; 925 Busse Road Elk Grove Village, IL 60007 (US) (For All Designated States Except US).
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY [US/US]; Asb III 3 Rutgers Plaza New Brunswick, NJ 08901 (US) (For All Designated States Except US).
THE OHIO STATE UNIVERSITY [US/US]; 1960 Kenny Road Columbus, OH 43210 (US) (For All Designated States Except US).
JARECKI, Jill [US/US]; (US) (For US Only).
SINGH, Jasbir [US/US]; (US) (For US Only).
GURNEY, Mark [US/US]; (US) (For US Only).
POLLOK, Brian, A. [US/US]; (US) (For US Only).
MICHAUD, Gregory [US/US]; (US) (For US Only).
LIU, Shin-Wu [--/US]; (US) (For US Only).
KILEDJIAN, Megerditch [US/US]; (US) (For US Only).
BUTCHBACH, Matthew [US/US]; (US) (For US Only).
BURGHES, Arthur [GB/US]; (US) (For US Only)
Inventors: JARECKI, Jill; (US).
SINGH, Jasbir; (US).
GURNEY, Mark; (US).
POLLOK, Brian, A.; (US).
MICHAUD, Gregory; (US).
LIU, Shin-Wu; (US).
KILEDJIAN, Megerditch; (US).
BUTCHBACH, Matthew; (US).
BURGHES, Arthur; (US)
Agent: BONE, Richard, G. A.; (US)
Priority Data:
61/072,040 26.03.2008 US
Abstract: front page image
(EN)The disclosure relates to methods and compositions (e.g., compounds and pharmaceutical compositions thereof) useful for increasing expression of SMN in a cell (e.g., in vitro or in vivo). As a deficiency in SMN can result in the development of an SMA condition in a subject, the methods and compositions described herein can also be used to, e.g., treat, or prevent, an SMA condition in a subject.
(FR)L'invention porte sur des procédés et des compositions (par exemple, des composés et des compositions pharmaceutiques de ceux-ci) utiles pour augmenter l'expression de SMN dans une cellule (par exemple, in vitro ou in vivo). Étant donné qu'une déficience en SMN peut conduire au développement d'une condition de SMA chez un sujet, les procédés et les compositions décrits ici peuvent également être utilisés, par exemple, pour traiter ou prévenir un état de SMA chez un sujet.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)