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Machine translation
1. (WO2009120619) NUCLEASE COMPOSITIONS, METHODS OF MAKING AND USING SUCH COMPOSITIONS, AND SYSTEMS FOR PULMONARY DELIVERY OF SUCH COMPOSITIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/120619    International Application No.:    PCT/US2009/037930
Publication Date: 01.10.2009 International Filing Date: 23.03.2009
IPC:
A61K 9/12 (2006.01), A61K 9/16 (2006.01), A61K 9/72 (2006.01), A61K 38/46 (2006.01)
Applicants: NOVARTIS AG [CH/CH]; Lichtstrasse 35 CH-4056 Basel (CH) (For All Designated States Except US).
WEERS, Jeffry, G. [US/US]; (US) (For US Only).
KUO, Mei-chang [US/US]; (US) (For US Only).
TARARA, Thomas [US/US]; (US) (For US Only)
Inventors: WEERS, Jeffry, G.; (US).
KUO, Mei-chang; (US).
TARARA, Thomas; (US)
Agent: KUNG, John, W.; (US)
Priority Data:
61/070,693 24.03.2008 US
Title (EN) NUCLEASE COMPOSITIONS, METHODS OF MAKING AND USING SUCH COMPOSITIONS, AND SYSTEMS FOR PULMONARY DELIVERY OF SUCH COMPOSITIONS
(FR) COMPOSITIONS DE NUCLÉASE, PROCÉDÉS DE PRÉPARATION ET D’UTILISATION DE CES COMPOSITIONS, ET SYSTÈMES D’ADMINISTRATION PULMONAIRE DE CES COMPOSITIONS
Abstract: front page image
(EN)A powder composition comprises particles including a nuclease, wherein the particles have a mass median aerodynamic diameter ranging from about 1 µm to about 5 µm. A pharmaceutical composition comprises a powder including an effective amount of nuclease and pharmaceutically acceptable excipient, wherein the powder comprises particles comprising less than 40 wt% of nuclease and having a mass median aerodynamic diameter ranging from about 1 µm to about 5 µm. Unit dosage forms, spray drying methods, and methods of treatment are also included.
(FR)L’invention concerne une composition en poudre comprenant des particules qui contiennent une nucléase, les particules ayant un diamètre aérodynamique massique médian compris entre environ 1 µm et environ 5 µm. L’invention concerne une composition pharmaceutique comprenant une poudre contenant une quantité efficace de nucléase et un excipient pharmaceutiquement acceptable, la poudre comprenant des particules qui contiennent moins de 40 % en poids de nucléase et ont un diamètre aérodynamique massique médian compris entre environ 1 µm et environ 5 µm. L’invention concerne également des formes pharmaceutiques unitaires, des procédés de séchage par atomisation et des méthodes de traitement.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)