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1. (WO2009119809) MARKER FOR DETERMINATION OF BREAST CANCER, TEST METHOD, AND TEST KIT

Pub. No.:    WO/2009/119809    International Application No.:    PCT/JP2009/056293
Publication Date: Oct 1, 2009 International Filing Date: Mar 27, 2009
IPC: C12Q 1/68
C12N 15/09
Applicants: KURODA, Masahiko
黒田 雅彦
miRacure, Inc.
株式会社ミラキュア
KONICA MINOLTA HOLDINGS, INC.
コニカミノルタホールディングス株式会社
TANAKA, Masami
田中 正視
OIKAWA, Kosuke
及川 恒輔
MIZUTANI, Takayuki
水谷 隆之
TAKANASHI, Masakatsu
高梨 正勝
Inventors: KURODA, Masahiko
黒田 雅彦
TANAKA, Masami
田中 正視
OIKAWA, Kosuke
及川 恒輔
MIZUTANI, Takayuki
水谷 隆之
TAKANASHI, Masakatsu
高梨 正勝
Title: MARKER FOR DETERMINATION OF BREAST CANCER, TEST METHOD, AND TEST KIT
Abstract:
Disclosed are: a maker which can detect the onset of breast cancer that cannot be detected by palpation or mammography test or the occurrence of early-stage (clinical stage 0) breast cancer, is convenient, and has high reliability; a test method; and a test kit. Specifically disclosed is a marker associated with breast cancer, which is characterized by comprising micro-RNA which is found in serum or plasma. More specifically, the marker comprises at least micro-RNA which exists in serum or plasma at a significantly reduced level after the onset of breast cancer or after the early stage (clinical stage 0) of breast cancer compared with that before the onset of breast cancer or before the early stage (clinical stage 0) of breast cancer.