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1. (WO2009118765) NOVEL MONOAMINE RE-UPTAKE INHIBITOR
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/118765    International Application No.:    PCT/IN2009/000202
Publication Date: 01.10.2009 International Filing Date: 27.03.2009
IPC:
C07D 217/16 (2006.01), C07D 401/04 (2006.01), C07D 401/06 (2006.01), C07D 405/04 (2006.01), C07D 409/04 (2006.01), C07D 409/06 (2006.01), C07D 411/12 (2006.01), C07D 413/12 (2006.01)
Applicants: PANACEA BIOTEC LIMITED [IN/IN]; B-1 Extn./A-27 Mohan Co-operative Industrial Estate Mathura Road New Delhi 110 044 (IN) (For All Designated States Except US).
KESSAR, Satinder, Vir [IN/IN]; (IN) (For US Only).
KULKARNI, Shrinivas, Krishnarao [IN/IN]; (IN) (For US Only).
JAIN, Rajesh [IN/IN]; (IN) (For US Only).
TREHAN, Sanjay [IN/IN]; (IN) (For US Only).
MAGADI, Sitaram, Kumar [IN/IN]; (IN) (For US Only).
DAS, Jagattaran [IN/IN]; (IN) (For US Only).
KAUR, Gurmeet [IN/IN]; (IN) (For US Only).
SINGH, Kamal, Nain [IN/IN]; (IN) (For US Only).
LATA, Sneh [IN/IN]; (IN) (For US Only).
DHIR, Ashish [IN/IN]; (IN) (For US Only)
Inventors: KESSAR, Satinder, Vir; (IN).
KULKARNI, Shrinivas, Krishnarao; (IN).
JAIN, Rajesh; (IN).
TREHAN, Sanjay; (IN).
MAGADI, Sitaram, Kumar; (IN).
DAS, Jagattaran; (IN).
KAUR, Gurmeet; (IN).
SINGH, Kamal, Nain; (IN).
LATA, Sneh; (IN).
DHIR, Ashish; (IN)
Agent: GUPTA, Bhartee; Panacea Biotec Limited, B - 1 Extn . /A- 27, Mohan Co-operative Industrial Estate , Mathura Road New Delhi 110044 (IN)
Priority Data:
821/DEL/2008 28.03.2008 IN
Title (EN) NOVEL MONOAMINE RE-UPTAKE INHIBITOR
(FR) NOUVEL INHIBITEUR DE RECAPTAGE DE MONOAMINE
Abstract: front page image
(EN)The present invention relates to novel compounds of Formula (I), their pharmaceutically acceptable derivatives, tautomeric forms, stereoisomers including R and S isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The invention also relates to the processes for the synthesis of novel compounds of Formula (I), their pharmaceutically acceptable derivatives, tautomeric forms, stereoisomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The present invention further provides pharmaceutical compositions comprising compounds of Formula (I) and methods of treating or preventing one or more disorders of the central and/or peripheral nervous system that are responsive to inhibition of biogenic amines, in particular one or more, or any combination of serotonin, norepinephrine and dopamine.
(FR)La présente invention concerne de nouveaux composés de formule (I), leurs dérivés pharmaceutiquement acceptables, formes tautomères, stéréo-isomères comprenant les isomères R et S, polymorphes, promédicaments, métabolites, sels ou solvates de ceux-ci. L'invention concerne en outre des procédés pour la synthèse de nouveaux composés de formule I, leurs dérivés pharmaceutiquement acceptables, formes tautomères, stéréo-isomères, polymorphes, promédicaments, métabolites, sels ou solvates de ceux-ci. La présente invention concerne en outre des compositions pharmaceutiques comprenant des composés de formule I et des procédés de traitement ou de prévention d'un ou plusieurs troubles du système nerveux central et/ou périphérique qui répondent à l'inhibition d'amines biogéniques, en particulier une ou plusieurs, ou une combinaison quelconque de la sérotonine, la norépinéphrine et la dopamine.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)