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Pub. No.:    WO/2009/106982    International Application No.:    PCT/IB2009/000432
Publication Date: 03.09.2009 International Filing Date: 26.02.2009
A61P 25/04 (2006.01), A61K 31/416 (2006.01), C07D 231/56 (2006.01), C07D 401/04 (2006.01), C07D 401/06 (2006.01), C07D 401/12 (2006.01), C07D 403/12 (2006.01), C07D 405/12 (2006.01), C07D 413/04 (2006.01), C07D 413/06 (2006.01), C07D 413/12 (2006.01), C07D 413/14 (2006.01), C07D 417/12 (2006.01), C07D 471/04 (2006.01), C07D 487/08 (2006.01)
Applicants: PFIZER INC. [US/US]; 235 East 42nd Street, New York, NY 10017 (US) (For All Designated States Except US).
BUCHLER, Ingrid, Price [US/US]; (US) (For US Only).
HAYES, Michael, Joseph [US/US]; (US) (For US Only).
HEGDE, Shridhar, Gajanan [US/US]; (US) (For US Only).
HOCKERMAN, Susan, Landis [US/US]; (US) (For US Only).
JONES, Darin, Eugene [US/US]; (US) (For US Only).
KORTUM, Steven, Wade [US/US]; (US) (For US Only).
RICO, Joseph, Gerace [US/US]; (US) (For US Only).
TENBRINK, Ruth, Elizabeth [US/US]; (US) (For US Only).
WU, Kun, Ken [CA/US]; (US) (For US Only)
Inventors: BUCHLER, Ingrid, Price; (US).
HAYES, Michael, Joseph; (US).
HEGDE, Shridhar, Gajanan; (US).
HOCKERMAN, Susan, Landis; (US).
JONES, Darin, Eugene; (US).
KORTUM, Steven, Wade; (US).
RICO, Joseph, Gerace; (US).
TENBRINK, Ruth, Elizabeth; (US).
WU, Kun, Ken; (US)
Agent: BENSON, Gregg, C.; c/o GEORGE, Nancy, McGraw Pfizer Inc. MS8260-1615 Eastern Point Road Groton, CT 06340 (US)
Priority Data:
61/032,657 29.02.2008 US
Abstract: front page image
(EN)This invention relates to compounds, pharmaceutical compositions and methods for the treatment of a condition mediated by CB1 receptor activity in a mammalian subject including a human, which comprises administering to a mammal in need of such treatment a therapeutically effective amount of the compound of formula (I) wherein R1, R2 and R3 are as defined in this specification.
(FR)Cette invention concerne des composés, des compositions pharmaceutiques et des méthodes de traitement d'une pathologie induite par l'activité du récepteur CB1 chez un mammifère, notamment chez l'homme. Ces méthodes consistent à administrer à un mammifère nécessitant un tel traitement une quantité thérapeutiquement efficace du composé de formule (I), dans laquelle R1, R2 et R3 sont tels que définis dans la description.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)