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1. (WO2009098612) POLYMORPHIC FORM OF A [1, 2, 4] TRIAZOLO [4, 3-A] PYRIDINE DERIVATIVE FOR TREATING INFLAMMATORY DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/098612    International Application No.:    PCT/IB2009/050351
Publication Date: 13.08.2009 International Filing Date: 28.01.2009
Chapter 2 Demand Filed:    06.10.2009    
IPC:
A61K 31/437 (2006.01), A61P 29/00 (2006.01), C07D 471/04 (2006.01)
Applicants: PFIZER LIMITED [GB/GB]; Ramsgate Road Sandwich Kent CT13 9NJ (GB) (For All Designated States Except US).
BUTCHER, Kenneth, John [GB/GB]; (GB) (For US Only)
Inventors: BUTCHER, Kenneth, John; (GB)
Agent: DROUIN, Stephane; (GB)
Priority Data:
61/025,879 04.02.2008 US
Title (EN) POLYMORPHIC FORM OF A [1, 2, 4] TRIAZOLO [4, 3-A] PYRIDINE DERIVATIVE FOR TREATING INFLAMMATORY DISEASES
(FR) FORME POLYMORPHE
Abstract: front page image
(EN)The present invention relates to a polymorphic form B of Λ/-[3-tert-butyl-1-(3- chloro-4-hydroxyphenyl)-1 H-pyrazol-5-yl]-N-{2-[(3-{2-[(2-hydroxyethyl)sulfanyl] phenyl}[1,2.4]triazolo[4,3-a]pyridin-6-yl)sulfanyl]benzyl}urea (I) as defined herein. This polymorph is useful in the treatment of various conditions, particularly in the treatment of inflammatory conditions such as chronic obstructive pulmonary disease.
(FR)Cette invention concerne une forme polymorphe B de N-[3-tert-butyl-1-(3-chloro-4-hydroxyphényl)-1H-pyrazol-5-yl]-N'-{2-[(3-{2-[(2-hydroxyéthyl)sulfanyl] phényl}[1,2,4]triazolo[4,3-a]pyridin-6-yl)sulfanyl]benzyl}urée comme défini ici. Cette forme polymorphe est utilisée dans le traitement de différentes pathologies, en particulier dans le traitement des maladies inflammatoires comme la bronchopneumopathie chronique obstructive.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)