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1. (WO2009098448) COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2009/098448 International Application No.: PCT/GB2009/000298
Publication Date: 13.08.2009 International Filing Date: 04.02.2009
IPC:
C07D 498/10 (2006.01) ,A61K 31/357 (2006.01) ,A61P 11/06 (2006.01) ,A61P 11/08 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
498
Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
02
in which the condensed system contains two hetero rings
10
Spiro-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
357
having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
06
Antiasthmatics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
08
Bronchodilators
Applicants:
ALCARAZ, Lilian [FR/GB]; GB (UsOnly)
BAILEY, Andrew [GB/GB]; GB (UsOnly)
BULL, Richard, James [GB/GB]; GB (UsOnly)
JOHNSON, Timothy [GB/GB]; GB (UsOnly)
KINDON, Nicholas, David [GB/GB]; GB (UsOnly)
LISTER, Andrew, Stuart [GB/GB]; GB (UsOnly)
ROBBINS, Andrew, James [GB/GB]; GB (UsOnly)
STOCKS, Michael, John [GB/GB]; GB (UsOnly)
TEOBALD, Barry, John [GB/GB]; GB (UsOnly)
ASTRAZENECA AB [SE/SE]; S-151 85 Sodertalje, SE (AllExceptUS)
PULMAGEN THERAPEUTICS (SYNERGY) LIMITED [GB/GB]; 8/9 Spire Green Centre Flex Meadow Harlow Essex CM19 5TR, GB (AllExceptUS)
Inventors:
ALCARAZ, Lilian; GB
BAILEY, Andrew; GB
BULL, Richard, James; GB
JOHNSON, Timothy; GB
KINDON, Nicholas, David; GB
LISTER, Andrew, Stuart; GB
ROBBINS, Andrew, James; GB
STOCKS, Michael, John; GB
TEOBALD, Barry, John; GB
Agent:
PHILLIPS, Neil; AstraZeneca AB AstraZeneca Intellectual Property SE-151 85 Södertäje, SE
Priority Data:
0802192.506.02.2008GB
0822437.O09.12.2008GB
Title (EN) COMPOUNDS
(FR) COMPOSÉS
Abstract:
(EN) Diazaspiro [5.5] undecane derivatives and related compounds as muscarinic-receptor antagonists and beta-adrenoceptor agonists for the treatment of pulmonary disorders.
(FR) La présente invention concerne des dérivés d'amides spirocycliques de formule I, des sels pharmaceutiquement acceptables de ceux-ci, un procédé pour leur préparation, des compositions pharmaceutiques les contenant, et leur utilisation en thérapie.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)