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1. WO2009098448 - COMPOUNDS

Publication Number WO/2009/098448
Publication Date 13.08.2009
International Application No. PCT/GB2009/000298
International Filing Date 04.02.2009
IPC
C07D 498/10 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
498Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
02in which the condensed system contains two hetero rings
10Spiro-condensed systems
A61K 31/357 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
357having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
A61P 11/06 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
A61P 11/08 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
08Bronchodilators
CPC
A61P 1/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
A61P 1/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
04for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A61P 1/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
16for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A61P 1/18
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
18for pancreatic disorders, e.g. pancreatic enzymes
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 11/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
02Nasal agents, e.g. decongestants
Applicants
  • ASTRAZENECA AB [SE]/[SE] (AllExceptUS)
  • PULMAGEN THERAPEUTICS (SYNERGY) LIMITED [GB]/[GB] (AllExceptUS)
  • ALCARAZ, Lilian [FR]/[GB] (UsOnly)
  • BAILEY, Andrew [GB]/[GB] (UsOnly)
  • BULL, Richard, James [GB]/[GB] (UsOnly)
  • JOHNSON, Timothy [GB]/[GB] (UsOnly)
  • KINDON, Nicholas, David [GB]/[GB] (UsOnly)
  • LISTER, Andrew, Stuart [GB]/[GB] (UsOnly)
  • ROBBINS, Andrew, James [GB]/[GB] (UsOnly)
  • STOCKS, Michael, John [GB]/[GB] (UsOnly)
  • TEOBALD, Barry, John [GB]/[GB] (UsOnly)
Inventors
  • ALCARAZ, Lilian
  • BAILEY, Andrew
  • BULL, Richard, James
  • JOHNSON, Timothy
  • KINDON, Nicholas, David
  • LISTER, Andrew, Stuart
  • ROBBINS, Andrew, James
  • STOCKS, Michael, John
  • TEOBALD, Barry, John
Agents
  • PHILLIPS, Neil
Priority Data
0802192.506.02.2008GB
0822437.O09.12.2008GB
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) COMPOUNDS
(FR) COMPOSÉS
Abstract
(EN) Diazaspiro [5.5] undecane derivatives and related compounds as muscarinic-receptor antagonists and beta-adrenoceptor agonists for the treatment of pulmonary disorders.
(FR) La présente invention concerne des dérivés d'amides spirocycliques de formule I, des sels pharmaceutiquement acceptables de ceux-ci, un procédé pour leur préparation, des compositions pharmaceutiques les contenant, et leur utilisation en thérapie.
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