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1. WO2009076465 - METHODS AND SYSTEMS FOR MAGNETIC FOCUSING OF THERAPEUTIC, DIAGNOSTIC OR PROPHYLACTIC AGENTS TO DEEP TARGETS

Publication Number WO/2009/076465
Publication Date 18.06.2009
International Application No. PCT/US2008/086276
International Filing Date 10.12.2008
IPC
A61M 37/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
37Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
CPC
A61B 5/055
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; ; Measuring using microwaves or radiowaves
055involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
A61B 5/411
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
41Detecting, measuring or recording for evaluating the immune or lymphatic systems
411Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
A61M 31/002
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
31Devices for introducing or retaining media, e.g. remedies, in cavities of the body
002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
A61N 2/002
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
2Magnetotherapy
002in combination with another treatment
A61P 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants
  • UNIVERSITY OF MARYLAND, COLLEGE PARK [US]/[US] (AllExceptUS)
  • SHAPIRO, Benjamin [US]/[US] (UsOnly)
  • LUBBE, Andreas [DE]/[DE] (UsOnly)
  • DIVER, Declan [GB]/[GB] (UsOnly)
  • POTTS, Hugh [GB]/[GB] (UsOnly)
  • PROBST, Roland [DE]/[DE] (UsOnly)
Inventors
  • SHAPIRO, Benjamin
  • LUBBE, Andreas
  • DIVER, Declan
  • POTTS, Hugh
  • PROBST, Roland
Agents
  • AUERBACH, Jeffrey, I.
Priority Data
60/996,93111.12.2007US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS AND SYSTEMS FOR MAGNETIC FOCUSING OF THERAPEUTIC, DIAGNOSTIC OR PROPHYLACTIC AGENTS TO DEEP TARGETS
(FR) PROCÉDÉS ET SYSTÈMES DE CONCENTRATION MAGNÉTIQUE D'AGENTS THÉRAPEUTIQUES, DIAGNOSTIQUES OU PROPHYLACTIQUES SUR DES CIBLES PROFONDES
Abstract
(EN)
Systems and methods are disclosed for trapping or focusing magnetizable particles comprising therapeutic agents at a distance using a dynamic magnetic field and feedback control, to enable the treatment of diseased areas deep inside a patient's body. The methods may be used to diagnose or treat diseased areas deep within a patient, for example tumors of the lungs, intestines, and liver, and is also useful in enhancing the permeability of solid tumors to chemotherapeutic agents.
(FR)
Cette invention concerne des systèmes et des procédés de piégeage ou de concentration de particules magnétisables comprenant des agents thérapeutiques à une certaine distance en utilisant un champ magnétique dynamique et un rétrocontrôle, pour permettre de traiter des zones atteintes et profondes dans l'organisme du patient. Les procédés peuvent être utilisés pour diagnostiquer ou traiter les zones atteintes profondes dans l'organisme du patient, par exemple des tumeurs du poumon, des intestins et du foie et sont également utilisés pour améliorer la perméabilité des tumeurs solides aux agents thérapeutiques.
Also published as
Latest bibliographic data on file with the International Bureau