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1. (WO2009071990) NO-DONATING CORDICOSTEROID WITH IMPROVED PHARMACOKINETIC, ANTI-INFLAMMATORY AND VASODILATORY PROPERTIES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2009/071990 International Application No.: PCT/IB2008/003433
Publication Date: 11.06.2009 International Filing Date: 08.08.2008
IPC:
A61K 31/58 (2006.01) ,A61K 9/72 (2006.01) ,A61P 11/00 (2006.01) ,A61P 11/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
56
Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
58
containing heterocyclic rings, e.g. aldosterone, danazol, stanozolol, pancuronium, digitogenin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
72
for smoking or inhaling
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
06
Antiasthmatics
Applicants:
TOPIGEN PHARMACEUTICALS INC. [CA/CA]; 4050 Molson Street, Suite 300 Montreal, H1Y 3N1, CA (AllExceptUS)
RENZI, Paolo [CA/CA]; CA (UsOnly)
PAGEAU, René [CA/CA]; CA (UsOnly)
PARRY-BILLINGS, Mark [CA/CA]; CA (UsOnly)
Inventors:
RENZI, Paolo; CA
PAGEAU, René; CA
PARRY-BILLINGS, Mark; CA
Priority Data:
60/969,24431.08.2007US
61/065,39608.02.2008US
61/065,39808.02.2008US
61/065,39908.02.2008US
Title (EN) NO-DONATING CORDICOSTEROID WITH IMPROVED PHARMACOKINETIC, ANTI-INFLAMMATORY AND VASODILATORY PROPERTIES
(FR) CORTICOSTÉROÏDE DONNEUR DE NO DOTÉ DE PROPRIÉTÉS PHARMACOCINÉTIQUES, ANTI-INFLAMMATOIRES ET VASODILATATRICES AMÉLIORÉES
Abstract:
(EN) The present invention involves the use of a steroid linked to nitric oxide (preferred steroid is budesonide) for treating respirator}' diseases by decreasing neutrophil sputum levels and decreasing plasma CRP levels Respiratory diseases treated include asthma, COPD (chronic obstructive pulmonary disorder), eosinophilic cough, bronchitis, sarcoidosis, pulmonary fibrosis, rhinitis, pulmonary hypertension, cystic fibrosis, bronchiectasis and sinusitis
(FR) L'invention concerne des procédés de traitement et des compositions de substances donneuses d'acide nitrique pour le traitement de maladies respiratoires et de conditions associées.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)