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1. (WO2009067663) ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/067663    International Application No.:    PCT/US2008/084345
Publication Date: 28.05.2009 International Filing Date: 21.11.2008
IPC:
A61K 47/48 (2006.01), A61K 49/10 (2006.01), C07C 35/37 (2006.01), C07C 49/683 (2006.01), C07C 211/42 (2006.01), C07C 251/44 (2006.01), C07D 249/18 (2006.01), C07D 263/52 (2006.01), C07D 271/12 (2006.01)
Applicants: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. [US/US]; Boyd Graduate Studies Research Center, Athens, GA 30602-7411 (US) (For All Designated States Except US).
BOONS, Geert-Jan [NL/US]; (US) (For US Only).
GUO, Jun [CN/US]; (US) (For US Only).
NING, Xinghai [CN/US]; (US) (For US Only).
WOLFERT, Margaretha [NL/US]; (US) (For US Only)
Inventors: BOONS, Geert-Jan; (US).
GUO, Jun; (US).
NING, Xinghai; (US).
WOLFERT, Margaretha; (US)
Agent: ALBIN, Loren, D.; Mueting, Raasch & Gebhardt, P.A., P.O. Box 581336, Minneapolis, MN 55458-1336 (US)
Priority Data:
61/004,021 21.11.2007 US
61/007,674 14.12.2007 US
61/137,061 25.07.2008 US
Title (EN) ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS
(FR) ALCYNES ET PROCÉDÉS DE RÉACTION D'ALCYNES AVEC DES COMPOSÉS DIPOLAIRES-1,3 FONCTIONNELS
Abstract: front page image
(EN)1,3-Dipole-functional compounds (e.g., azide functional compounds) can be reacted with certain alkynes in a cyclization reaction to form heterocyclic compounds. Useful alkynes (e.g., strained, cyclic alkynes) and methods of making such alkynes are also disclosed. The reaction of 1,3-dipole-functional compounds with alkynes can be used for a wide variety of applications including the immobilization of biomolecules on a substrate.
(FR)On peut faire réagir des composés dipolaires-1,3 fonctionnels (par ex., des composés fonctionnels d'azoture) avec certains alcynes dans une réaction de cyclisation pour former des composés hétérocycliques. L'invention concerne également des alcynes utiles (par ex., alcynes contraints, cycliques) et des procédés de fabrication de tels alcynes. La réaction de composés dipolaires-1,3 fonctionnels avec des alcynes peut être utilisée pour une grande variété d'applications, y compris l'immobilisation de biomolécules sur un substrat.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)