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1. (WO2009067647) CARBOCYCLIC ALPHA-L-BICYCLIC NUCLEIC ACID ANALOGS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/067647    International Application No.:    PCT/US2008/084299
Publication Date: 28.05.2009 International Filing Date: 21.11.2008
IPC:
C07H 21/00 (2006.01)
Applicants: ISIS PHARMACEUTICALS, INC. [US/US]; 1896 Rutherford Road Carlsbad, CA 92008 (US) (For All Designated States Except US).
SETH, Punit, P. [IN/US]; (US) (For US Only).
SWAYZE, Eric, E. [US/US]; (US) (For US Only)
Inventors: SETH, Punit, P.; (US).
SWAYZE, Eric, E.; (US)
Agent: REIGER, Dale; Jones Day 222 East 41st Street New York, NY 10017 (US)
Priority Data:
60/989,574 21.11.2007 US
61/056,564 28.05.2008 US
Title (EN) CARBOCYCLIC ALPHA-L-BICYCLIC NUCLEIC ACID ANALOGS
(FR) ANALOGUES D'ACIDE NUCLÉIQUE ALPHA-L-BICYCLIQUE CARBOCYCLIQUE
Abstract: front page image
(EN)The present invention provides novel carbocyclic α-L-bicyclic nucleosides and oligomeric compounds comprising at least one of these carbocyclic α-L-bicyclic nucleosides. The carbocyclic α-L-bicyclic nucleosides are useful for enhancing one or more properties of the oligomeric compounds they are incorporated into including nuclease resistance.
(FR)L'invention concerne de nouveaux nucléosides a-L-bicycliques carbocycliques et des composés oligomères comprenant au moins un de ces nucléosides a-L-bicycliques carbocycliques. Les nucléosides a-L-bicycliques carbocycliques sont utiles pour amplifier une ou plusieurs propriétés des composés oligomères qui sont incorporés à l'intérieur, y compris la résistance aux nucléases.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)