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1. (WO2009067081) PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF ASTHMA, COPD, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS, ATOPIC DERMATITIS, CANCER, HEPATITIS B, HEPATITIS C, HIV, HPV, BACTERIAL INFECTIONS AND DERMATOSIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/067081    International Application No.:    PCT/SE2008/051334
Publication Date: 28.05.2009 International Filing Date: 21.11.2008
IPC:
C07D 239/48 (2006.01), A61K 31/505 (2006.01), A61P 11/00 (2006.01), A61P 17/00 (2006.01), A61P 27/14 (2006.01), A61P 31/00 (2006.01), A61P 35/00 (2006.01), C07D 239/49 (2006.01), C07D 401/10 (2006.01), C07D 401/12 (2006.01), C07D 403/10 (2006.01), C07D 403/12 (2006.01), C07D 417/10 (2006.01)
Applicants: ASTRAZENECA AB [SE/SE]; S-151 85 Södertälje (SE) (For All Designated States Except US).
DAINIPPON SUMITOMO PHARMA CO., LTD [JP/JP]; 6-8, Dosho-machi 2-chome, Chuo-ku, Osaka-shi, Osaka-fu, Osaka 5418524 (JP) (For All Designated States Except US).
BENNETT, Nicholas, J. [GB/GB]; (GB) (For US Only).
MCINALLY, Thomas [GB/GB]; (GB) (For US Only).
MOCHEL, Tobias [DE/GB]; (GB) (For US Only).
THOM, Stephen [GB/GB]; (GB) (For US Only).
TIDÉN, Anna-Karin [SE/GB]; (GB) (For US Only)
Inventors: BENNETT, Nicholas, J.; (GB).
MCINALLY, Thomas; (GB).
MOCHEL, Tobias; (GB).
THOM, Stephen; (GB).
TIDÉN, Anna-Karin; (GB)
Agent: ASTRAZENECA AB; AstraZeneca Intellectual Property S-151 85 Södertälje (SE)
Priority Data:
0702577-8 22.11.2007 SE
61/013,699 14.12.2007 US
Title (EN) PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF ASTHMA, COPD, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS, ATOPIC DERMATITIS, CANCER, HEPATITIS B, HEPATITIS C, HIV, HPV, BACTERIAL INFECTIONS AND DERMATOSIS
(FR) DÉRIVÉS DE PYRIMIDINE POUR LE TRAITEMENT DE L'ASTHME, DE LA BRONCHO-PNEUMOPATHIE CHRONIQUE OBSTRUCTIVE (COPD), DE LA RHINITE ALLERGIQUE, DE LA CONJONCTIVITE ALLERGIQUE, DE LA DERMATITE ATOPIQUE, DU CANCER, DE L'HÉPATITE B, DE L'HÉPATITE C, DU VIH, DU VPP, DES INFECTIONS BACTÉRIENNES ET DE LA DERMATOSE
Abstract: front page image
(EN)The present invention provides compounds of formula (I) wherein R 1, R2, R3 and R4 are as defined in the specification, and pharmaceutically acceptable salts thereof, as well as processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
(FR)La présente invention propose des composés représentés par la formule (I) dans laquelle R1, R2, R3 et R4 sont tels que définis dans la description, et sur des sels acceptables de ceux-ci du point de vue pharmaceutique, ainsi que des procédés pour leur préparation, des compositions pharmaceutiques les contenant et leur utilisation en thérapie.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)