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1. (WO2009066879) ORGANIC-INORGANIC HYBRID SCAFFOLDS WITH SURFACE-IMMOBILIZED NANO-HYDROXYAPATITE AND PREPARATION METHOD THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/066879    International Application No.:    PCT/KR2008/006349
Publication Date: 28.05.2009 International Filing Date: 28.10.2008
IPC:
A61L 27/48 (2006.01)
Applicants: KOREA INSTITUTE OF CERAMIC ENGINEERING & TECHNOLOGY [KR/KR]; 233-5, Gasan-dong, Geumcheon-gu, Seoul 153-801 (KR) (For All Designated States Except US).
LEE, Sang Cheon [KR/KR]; (KR) (For US Only).
KIM, Kyung Ja [KR/KR]; (KR) (For US Only).
KIM, Sung Eun [KR/KR]; (KR) (For US Only).
HWANG, Ho Chan [KR/KR]; (KR) (For US Only).
KANG, Ke-Won [KR/KR]; (KR) (For US Only).
SEO, Seog-Jin [KR/KR]; (KR) (For US Only).
KIM, Jin-Young [KR/KR]; (KR) (For US Only).
CHANG, Jeong HO [KR/KR]; (KR) (For US Only).
LEE, Jin Hyung [KR/KR]; (KR) (For US Only)
Inventors: LEE, Sang Cheon; (KR).
KIM, Kyung Ja; (KR).
KIM, Sung Eun; (KR).
HWANG, Ho Chan; (KR).
KANG, Ke-Won; (KR).
SEO, Seog-Jin; (KR).
KIM, Jin-Young; (KR).
CHANG, Jeong HO; (KR).
LEE, Jin Hyung; (KR)
Agent: SON, Min; 6th floor, City Air Tower 159-9, Samseong-dong, Gangnam-gu, Seoul 135-973 (KR)
Priority Data:
10-2007-0118713 20.11.2007 KR
Title (EN) ORGANIC-INORGANIC HYBRID SCAFFOLDS WITH SURFACE-IMMOBILIZED NANO-HYDROXYAPATITE AND PREPARATION METHOD THEREOF
(FR) ECHAFAUDAGES HYBRIDES ORGANIQUES-INORGANIQUES À NANO-HYDROXYAPATITE IMMOBILISÉE EN SURFACE ET LEUR PROCÉDÉ DE FABRICATION
Abstract: front page image
(EN)Provided are an organic-inorganic hybrid scaffold with surface-immobilized nano-hydroxyapatite, and a method for the fabrication thereof. The scaffold is fabricated by reacting an acid group present on a surface of nano-hydroxyapatite with a primary amine present on a surface of a polymer support in the presence of EDC (l-ethyl-3-dimethylaminopropyl carbodiimide) to immobilize nano-hydroxyapatite onto the surface of the polymer support. The surface of nano-hydroxyapatite is previously grafted with poly (ethylene glycol methacrylate phosphate) (PoIyEGMP) having phosphonic acid functionality or with a polymer having carboxylic acid functionality.
(FR)L'invention porte sur un échafaudage hybride organique-inorganique à nano-hydroxyapatite immobilisée en surface et sur son procédé de fabrication. Ledit échafaudage est fabriqué par réaction d'un groupe acide présent sur une surface de nano-hydroxyapatite renfermant une amine primaire sur la surface d'un support polymérique en présence d'EDC (1-éthyl-3-diméthylaminopropylcarbodiimide) pour immobiliser de la nano-hydroxyapatite sur la surface du support polymérique. La surface de nano-hydroxyapatite est préalablement greffée par du poly(éthylèneglycol méthacrylate phosphate) (PolyEGMP) possédant une fonctionnalité acide phosphonique ou avec un polymère possédant une fonctionnalité acide carboxylique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: Korean (KO)