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1. (WO2009065797) PROCESS FOR OBTAINING MIXTURES OF 4-CARBOXY-1,3-THIAZOLIDINIUM CARBOXYLATE AND N-ACYL-1,3-THIAZOLIDIN-4-CARBOXYLIC ACID
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/065797    International Application No.:    PCT/EP2008/065652
Publication Date: 28.05.2009 International Filing Date: 17.11.2008
Chapter 2 Demand Filed:    22.09.2009    
IPC:
C07D 277/04 (2006.01)
Applicants: UNIVERSITAT DE LLEIDA [ES/ES]; Pl. de Victor Siurana, 1 E-25003 Lleida (ES) (For All Designated States Except US).
AXEB BIOTECH, S. L. [ES/ES]; C. Valencia, 264, 2n., E-08007 Barcelona (ES) (For All Designated States Except US).
CANELA GARAYOA, Ramon [ES/ES]; (ES) (For US Only).
BALCELLS FLUVIA, Merce [ES/ES]; (ES) (For US Only).
ERAS JOLI, Jorge [ES/ES]; (ES) (For US Only).
HIJOS BITRIAN, Javier Maria [ES/ES]; (ES) (For US Only).
LLOVERA ARCAS, Montserrat [ES/ES]; (ES) (For US Only)
Inventors: CANELA GARAYOA, Ramon; (ES).
BALCELLS FLUVIA, Merce; (ES).
ERAS JOLI, Jorge; (ES).
HIJOS BITRIAN, Javier Maria; (ES).
LLOVERA ARCAS, Montserrat; (ES)
Agent: PONTI SALES, Adelaida; C. Consell de Cent, 322 E-08007 Barcelona (ES)
Priority Data:
P-200703090 23.11.2007 ES
Title (EN) PROCESS FOR OBTAINING MIXTURES OF 4-CARBOXY-1,3-THIAZOLIDINIUM CARBOXYLATE AND N-ACYL-1,3-THIAZOLIDIN-4-CARBOXYLIC ACID
(FR) PROCÉDÉ D'OBTENTION DE MÉLANGES DE CARBOXYLATE DE 4-CARBOXY-1,3-THIAZOLIDINIUM ET D'ACIDE N-ACYL-1,3-THIAZOLIDIN-4-CARBOXYLIQUE
Abstract: front page image
(EN)The present invention relates to a process for obtaining in a single synthesis stage mixtures of 4-carboxy-1,3-thiazolidium carboxylate and N-acyl-1, 3-thiazolidin-4- carboxylic acids from 1,3-thiazolidin-4-carboxylic acids and derivatives of carboxylic acids, which has the following advantages: use of environmentally friendly solvents, lower energy consumption, lower consumption of acylating reagents, which allows the corresponding mixtures to be obtained with suitable characteristics and specifications, ease of recovery from the reaction medium and high yields.
(FR)La présente invention concerne un procédé permettant d'obtenir en une seule étape de synthèse des mélanges de carboxylate de 4-carboxy-1, 3- thiazolidium et d'acide N-acyl-1, 3-thiazolidin-4- carboxylique à partir d'acides 1, 3-thiazolidin-4-carboxyliques et de dérivés d'acides carboxyliques, qui présente les avantages suivants : utilisation de solvants écologiques, baisse de la consommation d'énergie, baisse de la consommation de réactifs d'acylation, ce qui permet l'obtention de mélanges correspondants aux caractéristiques et spécifications appropriées, une récupération facile à partir du milieu réactionnel et des rendements élevés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)