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1. (WO2009065141) METHODS AND COMPOSITIONS FOR REDUCING SKIN DAMAGE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/065141    International Application No.:    PCT/US2008/083829
Publication Date: 22.05.2009 International Filing Date: 17.11.2008
IPC:
A61K 48/00 (2006.01), A61K 6/00 (2006.01)
Applicants: THE GENERAL HOSPITAL CORPORATION [US/US]; 55 Fruit Street, Boston, Massachusetts 02114 (US) (For All Designated States Except US).
SHISEIDO CO., LTD. [JP/JP]; 2-12-1, Fukuura, Kanazawa-ku, Yokohama-shi, Kanagawa 103 (JP) (For All Designated States Except US).
LEE, Sam W. [US/US]; (US) (For US Only).
RAJ, Lakshmi [US/US]; (US) (For US Only).
MANDINOVA, Anna I. [US/US]; (US) (For US Only).
IWAKI, Haruhi [JP/JP]; (JP) (For US Only).
KATSUTA, Yuji [JP/JP]; (JP) (For US Only).
NAKANISHI, Jotaro [JP/JP]; (JP) (For US Only)
Inventors: LEE, Sam W.; (US).
RAJ, Lakshmi; (US).
MANDINOVA, Anna I.; (US).
IWAKI, Haruhi; (JP).
KATSUTA, Yuji; (JP).
NAKANISHI, Jotaro; (JP)
Agent: MCQUADE, Ryan; Fish & Richardson P.C., P.O. Box 1022, Minneapolis, Minnesota 55440-1022 (US)
Priority Data:
61/003,351 15.11.2007 US
Title (EN) METHODS AND COMPOSITIONS FOR REDUCING SKIN DAMAGE
(FR) PROCÉDÉS ET COMPOSITIONS DE RÉDUCTION DES LÉSIONS CUTANÉES
Abstract: front page image
(EN)The RhoE GTPase pathway has been identified as a target for screening and treatment methods for the prevention and/or reduction of short- and long-term UVB-induced skin damage, e.g., the prevention and/or reduction of UVB-induced wrinkles. The invention thus features screening and treatment methods for prevention or reduction of UVB-induced sin damage, and related compositions, e.g., cosmetic compositions.
(FR)La voie de la RhoE GTPase a été identifiée comme une cible pour des procédés de criblage et de traitement pour la prévention et/ou la réduction de lésions cutanées à court et long terme induites par les UVB, par exemple, la prévention et/ou la réduction des rides induites par les UVB. L'invention concerne par conséquent des procédés de criblage et de traitement pour la prévention et la réduction de lésions cutanées induites par les UVB, et des compositions apparentées, par exemple, des compositions cosmétiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)