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Machine translation
1. (WO2009065098) USE OF CATHEPSIN K ANTAGONISTS IN THE TREATMENT OF BONE CANCER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/065098    International Application No.:    PCT/US2008/083722
Publication Date: 22.05.2009 International Filing Date: 17.11.2008
IPC:
A61K 38/00 (2006.01), A01N 43/04 (2006.01), A61K 31/497 (2006.01), A61K 39/395 (2006.01)
Applicants: VELCURA THERAPEUTICS, INC. [US/US]; 4300 Varsity Drive, Suite D, Ann Arbor, MI 48108 (US) (For All Designated States Except US).
LONG, Michael [US/US]; (US) (For US Only).
CHAGNOVICH, Daniel [US/US]; (US) (For US Only)
Inventors: LONG, Michael; (US).
CHAGNOVICH, Daniel; (US)
Agent: HIGHLANDER, Steven, L.; Fulbright & Jaworski L.L.P., 600 Congress Avenue, Suite 2400, Austin, TX 78701 (US)
Priority Data:
60/988,634 16.11.2007 US
Title (EN) USE OF CATHEPSIN K ANTAGONISTS IN THE TREATMENT OF BONE CANCER
(FR) UTILISATION D'ANTAGONISTES DE LA CATHEPSINE K DANS LE TRAITEMENT DU CANCER DES OS
Abstract: front page image
(EN)The invention regards the modulation of a proteolytic enzyme, Cathepsin K that results in increased bone production by bone-forming cells. Drugs that target this enzyme inhibit its activity represent a new class of therapies for multiple myeloma.
(FR)La présente invention concerne la modulation d'une enzyme protéolytique, la cathepsine K qui entraîne une augmentation de la production osseuse par les cellules fabriquant l'os. Les médicaments qui ciblent cette enzyme pour inhiber son activité représentent une nouvelle classe de thérapie pour le myélome multiple.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)