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Machine translation
1. (WO2009064493) TRICYCLIC COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/064493    International Application No.:    PCT/US2008/012838
Publication Date: 22.05.2009 International Filing Date: 14.11.2008
IPC:
A61K 31/137 (2006.01), A61K 31/335 (2006.01), A61K 31/55 (2006.01), A61K 45/06 (2006.01), A61P 17/00 (2006.01)
Applicants: NEW YORK UNIVERSITY SCHOOL OF MEDICINE [US/US]; 650 First Avenue, New York, NY 10016 (US) (For All Designated States Except US).
ORLOW, Seth, J. [US/US]; (US) (For US Only).
KOMATSU, Li, Ni [US/US]; (US) (For US Only)
Inventors: ORLOW, Seth, J.; (US).
KOMATSU, Li, Ni; (US)
Agent: JACKSON, David, A.; Klauber & Jackson, 411 Hackensack Avenue, Hackensack, NJ 07601 (US)
Priority Data:
60/988,094 14.11.2007 US
Title (EN) TRICYCLIC COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF
(FR) COMPOSÉS TRICYCLIQUES EN TANT QUE MODIFICATEURS DE LA MÉLANOGENÈSE ET LEURS UTILISATIONS
Abstract: front page image
(EN)A method of identification of tricyclic compounds (formula I) that control melanin synthesis (melanogenesis), and the use of such compounds and compositions thereof to modify (e.g., inhibit) melanin production are disclosed. Formula (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of conditions that are causally related to aberrant melanogenesis activity including by way of non-limiting example, hyperpigmentation and others.
(FR)L'invention concerne un procédé d'identification de composés tricycliques (formule I) qui contrôlent la synthèse de la mélanine (mélanogenèse), et l'utilisation de tels composés et de compositions associées pour modifier (par exemple, inhiber) la production de mélanine. Lesdits composés peuvent être préparés sous la forme de compositions pharmaceutiques et ils peuvent être utilisés pour la prévention et le traitement d'affections ayant pour cause une activité de mélanogenèse aberrante y compris à titre d'exemple non limitatif, une hyperpigmentation et autres.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)