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1. (WO2009064481) IDENTIFICATION OF NOVEL SUBGROUPS OF HIGH-RISK PEDIATRIC PRECURSOR B ACUTE LYMPHOBLASTIC LEUKEMIA, OUTCOME CORRELATIONS AND DIAGNOSTIC AND THERAPEUTIC METHODS RELATED TO SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/064481    International Application No.:    PCT/US2008/012821
Publication Date: 22.05.2009 International Filing Date: 14.11.2008
IPC:
C12Q 1/68 (2006.01), C12N 15/10 (2006.01), C12N 15/09 (2006.01)
Applicants: STC.UNM [US/US]; 801 University Blvd. SE, Suite 101, Albuquerque, NM 87106 (US) (For All Designated States Except US).
SANDIA CORPORATION [US/US]; P.O. Box 5800, Mail Stop 0141, Albuquerque, NM 87185 (US) (For All Designated States Except US).
WILLMAN, Cheryl, L. [US/US]; (US) (For US Only).
HARVEY, Richard [US/US]; (US) (For US Only).
DAVIDSON, George, S. [US/US]; (US) (For US Only).
WANG, Xuefei [CH/US]; (US) (For US Only).
ATLAS, Susan, R. [US/US]; (US) (For US Only).
BEDRICK, Edward, J. [US/US]; (US) (For US Only).
CHEN, Iming, M. [CN/US]; (US) (For US Only)
Inventors: WILLMAN, Cheryl, L.; (US).
HARVEY, Richard; (US).
DAVIDSON, George, S.; (US).
WANG, Xuefei; (US).
ATLAS, Susan, R.; (US).
BEDRICK, Edward, J.; (US).
CHEN, Iming, M.; (US)
Agent: COLEMAN, Henry, D.; Coleman Sudol Sapone, P.C., 714 Colorado Avenue, Bridgeport, CT 06605-1601 (US)
Priority Data:
61/003,048 14.11.2007 US
Title (EN) IDENTIFICATION OF NOVEL SUBGROUPS OF HIGH-RISK PEDIATRIC PRECURSOR B ACUTE LYMPHOBLASTIC LEUKEMIA, OUTCOME CORRELATIONS AND DIAGNOSTIC AND THERAPEUTIC METHODS RELATED TO SAME
(FR) IDENTIFICATION DE NOUVEAUX SOUS-GROUPES DE PATIENTS PÉDIATRIQUES À HAUT RISQUE DE LEUCÉMIE LYMPHOBLASTIQUE AIGUË À PRÉCURSEURS B, CORRÉLATIONS DES ISSUES ET PROCÉDÉS DIAGNOSTIQUES ET THÉRAPEUTIQUES S'Y RAPPORTANT
Abstract: front page image
(EN)The present invention relates to the identification of genetic markers patients with high risk B-precursor acute lymphoblastic leukemia (B-ALL) and associated methods and their relationship to therapeutic outcome. The present invention also relates to diagnostic, prognostic and related methods using these genetic markers, as well as kits which provide microchips and/or immunoreagents for performing analysis on leukemia patients.
(FR)La présente invention concerne l'identification de patients à marqueurs génétiques à haut risque de leucémie lymphoblastique aiguë à précurseurs B (B-ALL) et des procédés associés ainsi que leur relation à l'issue thérapeutique. La présente invention concerne également des procédés diagnostiques, pronostiques et autres procédés apparentés utilisant ces marqueurs génétiques, ainsi que des trousses contenant des micropuces et/ou des réactifs immunologiques pour effectuer l'analyse sur des patients leucémiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)