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Machine translation
1. (WO2009063243) DETECTION OF NEISSERIA MENINGITIDIS BY LOOP MEDIATED BY LOOP MEDIATED ISOTHERMAL AMPLIFICATION ASSAY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/063243    International Application No.:    PCT/GB2008/051061
Publication Date: 22.05.2009 International Filing Date: 14.11.2008
IPC:
C12Q 1/68 (2006.01)
Applicants: BELFAST HEALTH AND SOCIAL CARE TRUST [GB/GB]; Nore Villa, Knockbracken Healthcare Park, Saintfield Road, Belfast Down BT8 *BH (GB) (For All Designated States Except US).
COYLE, Peter [GB/GB]; (GB) (For US Only).
FAIRLEY, Derek [GB/GB]; (GB) (For US Only).
MCKENNA, James [IE/GB]; (GB) (For US Only)
Inventors: COYLE, Peter; (GB).
FAIRLEY, Derek; (GB).
MCKENNA, James; (GB)
Agent: MCNALLY, Roisin; IPEUS Limited, 22A Victoria Road, Holywood, Down BT18 9BG (GB)
Priority Data:
61/002,987 14.11.2007 US
Title (EN) DETECTION OF NEISSERIA MENINGITIDIS BY LOOP MEDIATED BY LOOP MEDIATED ISOTHERMAL AMPLIFICATION ASSAY
(FR) BIOESSAI
Abstract: front page image
(EN)The invention provides a LAMP assay for detection of meningococcal disease, the test comprising at least one nucleic acid primer set capable of detecting Neisseria meningitides in a LAMP based molecular test, the primer set being chosen from the primer sets listed in Table 1 as LAMP SETS 1 to 12 comprising SEQUENCE IDs from ID:1 to ID:69. Each assay consists of a primer set including of one pair of forward (FIP) and reverse (BIP) inner primers, forward (F3) and reverse (B3) outer primers. The assay may also include loop forward (LF) and/or loop back (LB) primers to accelerate the reaction. Neisseria meningitides serotypes A,B,C,Y and W135 can be detected using the assay of the invention.
(FR)L'invention porte sur un bioessai LAMP de détection de maladies à méningocoques, comprenant au moins un jeu d'amorces d'acides nucléiques pouvant détecter le Neisseria meningitides dans un bioessai moléculaire à base de LAMP, un tel jeu étant choisi parmi les jeux d'amorces listés dans la Table 1 en tant que LAMP SETS 1 à 12 comprenant les SEQUENCE ID de ID:1 à ID:69. Chaque bioessai consiste en un jeu d'amorces comprenant une paire d'amorces intérieures directes (FIP) et une paire d'amorces intérieures inverses (BIP), et des amorces extérieures directes (F3) et inverses (B3). Le bioessai peut également inclure des amorces boucles directes (LF) et/ou des amorces boucles inverses (LB) accélérant la réaction. Le bioessai permet en outre de détecter les sérotypes A,B,C,Y et W135 du Neisseria meningitides.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)