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Machine translation
1. (WO2009063226) METHODS RELATING TO BREATHING DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/063226    International Application No.:    PCT/GB2008/003856
Publication Date: 22.05.2009 International Filing Date: 12.11.2008
IPC:
A61P 11/00 (2006.01), A61K 31/00 (2006.01), A61K 31/18 (2006.01), A61K 31/341 (2006.01), A61K 31/405 (2006.01), A61K 31/415 (2006.01), A61K 31/42 (2006.01), A61K 49/00 (2006.01), G01N 33/68 (2006.01)
Applicants: SAMSARA MEDICIN AB [SE/SE]; Sturegatan 40 S-11436 Stockholm (SE) (For All Designated States Except US).
HERLENIUS, Eric [SE/SE]; (SE).
JAKOBSSON, Per-Johan [SE/SE]; (SE).
HOFSTETTER OLSSON, Annika [US/US]; (US).
CASLEY, Christopher, Stuart [GB/GB]; (GB) (MN only)
Inventors: HERLENIUS, Eric; (SE).
JAKOBSSON, Per-Johan; (SE).
HOFSTETTER OLSSON, Annika; (US)
Agent: MATTSSON, Niklas; Awapatent AB P.O. Box 45086 S-104 30 Stockholm (SE)
Priority Data:
60/987,217 12.11.2007 US
Title (EN) METHODS RELATING TO BREATHING DISORDERS
(FR) PROCÉDÉS SE RAPPORTANT À DES TROUBLES RESPIRATOIRES
Abstract: front page image
(EN)Methods for treating breathing disorders by inhibition of the induced PGE2 pathway in a mammalian subject, methods for assessing apnea, hypoxic ischemic encephalopathy or perinatal asphyxia by detecting an elevated level of PGE2, or a metabolite thereof, in a sample from the subject compared with a control level, and in vitro and in vivo screening methods for medicaments for treating breathing disorders are disclosed.
(FR)L'invention porte sur des procédés pour traiter des troubles respiratoires par l'inhibition de la voie de PGE2 induite chez un sujet mammifère, sur des procédés pour évaluer l'apnée, l'encéphalopathie ischémique hypoxique ou l'asphyxie périnatale par la détection d'un taux élevé de PGE2, ou d'un métabolite de celui-ci, dans un échantillon provenant du sujet par comparaison avec un taux témoin, et sur des procédés de criblage in vitro et in vivo pour des médicaments pour traiter des troubles respiratoires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)