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Machine translation
1. (WO2009062001) STIMULATION OF ANTI-TUMOR IMMUNITY USING DENDRITIC CELL/TUMOR CELL FUSIONS AND ANTI-CD3/CD28
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/062001    International Application No.:    PCT/US2008/082750
Publication Date: 14.05.2009 International Filing Date: 07.11.2008
IPC:
C12N 5/12 (2006.01), C12N 5/16 (2006.01), A61K 39/00 (2006.01), G01N 33/00 (2006.01)
Applicants: DANA-FARBER CANCER INSTITUTE, INC. [US/US]; 44 Binney Street, Boston, MA 02115 (US) (For All Designated States Except US).
BETH ISRAEL DEACONESS MEDICAL CENTER [US/US]; 330 Brookline Avenue, Boston, MA 02215 (US) (For All Designated States Except US).
AVIGAN, David [US/US]; (US) (For US Only).
KUFE, Donald [US/US]; (US) (For US Only)
Inventors: AVIGAN, David; (US).
KUFE, Donald; (US)
Agent: ELRIFI, Ivor, R.; Mintz, Levin, Cohn, Ferris, Glovsky And Popeo Pc, One Financial Center, Boston, MA 02111 (US)
Priority Data:
61/002,538 08.11.2007 US
Title (EN) STIMULATION OF ANTI-TUMOR IMMUNITY USING DENDRITIC CELL/TUMOR CELL FUSIONS AND ANTI-CD3/CD28
(FR) STIMULATION DE L'IMMUNITÉ ANTICANCÉREUSE À L'AIDE DE FUSIONS DE CELLULES DENDRITIQUES/CELLULES TUMORALES ET ANTI-CD3/CD28
Abstract: front page image
(EN)The invention is concerned with fusions of dendritic cells and with tumor or cancer cells. Also provided are methods of making and using these cell fusions, including methods of adoptive immunotherapy as well as methods of stimulating anti-tumor immunity using fused cells and anti-CD3/CD28 antibodies.
(FR)L'invention concerne des fusions de cellules dendritiques et de cellules présentant un antigène. Il est également proposé des procédés de fabrication et d'utilisation de ces fusions cellulaires, y compris des procédés d'immunothérapie adoptive de même que des procédés de stimulation de l'immunité anticancéreuse à l'aide de cellules fusionnées et d'anticorps anti-CD3/CD28.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)