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Machine translation
1. (WO2009060089) METHOD OF DIAGNOSIS AND SUBGROUP ANALYSIS IN SUBJECTS HAVING OR BEING SUSPECTED OF HAVING IRRITABLE BOWEL SYNDROME, NUCLEIC ACIDS AND KITS, AND THEIR USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/060089    International Application No.:    PCT/EP2008/065182
Publication Date: 14.05.2009 International Filing Date: 07.11.2008
IPC:
C12Q 1/68 (2006.01)
Applicants: UNIVERSITÄTSKLINIKUM HEIDELBERG [--/DE]; Im Neuenheimer Feld 672 69120 Heidelberg (DE) (For All Designated States Except US).
NIESLER, Beate [DE/DE]; (DE) (For US Only).
RAPPOLD, Gudrun [DE/DE]; (DE) (For US Only).
KAPELLER, Johannes [DE/DE]; (DE) (For US Only)
Inventors: NIESLER, Beate; (DE).
RAPPOLD, Gudrun; (DE).
KAPELLER, Johannes; (DE)
Agent: Patentanwälte Reitstötter Kinzebach; Sternwartstr. 4 81679 München (DE)
Priority Data:
60/986,638 09.11.2007 US
Title (EN) METHOD OF DIAGNOSIS AND SUBGROUP ANALYSIS IN SUBJECTS HAVING OR BEING SUSPECTED OF HAVING IRRITABLE BOWEL SYNDROME, NUCLEIC ACIDS AND KITS, AND THEIR USE
(FR) PROCÉDÉ DE DIAGNOSTIC ET D'ANALYSE DE SOUS-GROUPE DANS DES SUJETS AYANT OU ÉTANT SUSPECTÉS D'AVOIR LE SYNDROME DU CÔLON IRRITABLE, ACIDES NUCLÉIQUES ET KITS, ET LEUR UTILISATION
Abstract: front page image
(EN)Method of diagnosis and subgroup analysis in subjects having or being suspected of having Irritable Bowel Syndrome, nucleic acids and kits, and their use The invention relates to a method of diagnosis and subgroup analysis in subjects having or being suspected of having IrritableBowelSyndromebased on the detection of polymorphisms in serotonin type 3 receptor (5-HT3) genes. The invention relates to certain nucleic acids, in particular probes, and kits containing said nucleic acids. The methods, probes and kits are useful for diagnosing Irritable Bowel Syndrome and predicting the potential benefits of 5-HT3 receptor antagonist treatment.
(FR)L'invention concerne un procédé de diagnostic et d'analyse de sous-groupe dans des sujets ayant ou étant suspectés d'avoir le syndrome du côlon irritable, des acides nucléiques et des kits et leur utilisation. L'invention porte sur un procédé précité basé sur la détection de polymorphismes dans des gènes de récepteur de sérotonine de type 3 (5-HT3). L'invention porte sur certains acides nucléiques, en particulier des sondes, et sur des kits contenant lesdits acides nucléiques. Les procédés, sondes et coffrets sont utiles pour diagnostiquer le syndrome du côlon irritable et prédire les avantages potentiels d'un traitement par un antagoniste des récepteurs 5-HT3.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)