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1. (WO2009060073) USE OF OLIGOSACCHARIDES CONTAINING N-ACETYLLACTOSAMINE FOR MATURATION OF IMMUNE RESPONSES IN NEONATES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/060073    International Application No.:    PCT/EP2008/065143
Publication Date: 14.05.2009 International Filing Date: 07.11.2008
IPC:
A61K 31/7028 (2006.01), A23L 1/29 (2006.01), A23L 1/30 (2006.01), A23L 1/308 (2006.01), A61P 37/04 (2006.01), A61P 37/08 (2006.01), A61K 45/06 (2006.01)
Applicants: NESTEC S.A. [CH/CH]; Av. Nestlé 55, CH-1800 Vevey (CH) (For All Designated States Except US).
FICHOT, Marie-Claire [FR/CH]; (CH) (For US Only).
SPRENGER, Norbert [LI/CH]; (CH) (For US Only)
Inventors: FICHOT, Marie-Claire; (CH).
SPRENGER, Norbert; (CH)
Agent: DIXON, Sarah; Av. Nestlé 55, CH-1800 Vevey (CH)
Priority Data:
07120265.9 08.11.2007 EP
Title (EN) USE OF OLIGOSACCHARIDES CONTAINING N-ACETYLLACTOSAMINE FOR MATURATION OF IMMUNE RESPONSES IN NEONATES
(FR) MATURATION DE RÉPONSES IMMUNES DANS LES NOUVEAUX NÉS
Abstract: front page image
(EN)This invention relates to the use of an oligosaccharide selected from the group consisting of lactc -N-tetraose, lacio-N-neotetraose, lacto-N-hexaose, lacto-N-neohexaose, para-lacto-N-hexaose, para-lacto-N-neohexaose, lacto-N-octaose, lacto-N-neooctaose, iso- lacto-N-octaose, para- lacto-N-octaose and lacto-N-decaosein the manufacture of a medicament for infants or a therapeutic nutritional composition for infants for modulating immune responses in a neonatal infant. The invention extends to the use of such an oligosaccharide for modulating the immune system of a neonatal infant to promote the development in the first few weeks of the life of the infant of a beneficial intestinal microbiota comparable with that found in breast fed infants and for reducing the risk of subsequent development of allergy in the infant.
(FR)Utilisation d'oligosaccharide du groupe comprenant lactc -N-tétraose, lacio-N-neotétraose, lacto-N-hexaose, lacto-N-néohexaose, para-lacto-N-hexaose, para-lacto-N-néohexaose, lacto-N-octaose, lacto-N-néooctaose, iso- lacto-N-octaose, para- lacto-N-octaose et lacto-N-décaose, dans la fabrication de médicament pour nourrissons ou de composition nutritive thérapeutique pour enfants en bas âge permettant de moduler les réponses immunes chez les nouveaux nés. Par ailleurs, utilisation de cet oligosaccharide pour moduler le système immunitaire d'un nouveau né afin de promouvoir le développement de microbiote intestinal bénéfique au cours des premières semaines de vie, comparable avec un développement similaire constaté chez les enfants allaités au sein, et afin de réduire le risque de développement ultérieur d'allergie chez le nourrisson.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)