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1. (WO2009060071) INSULIN DERIVATIVE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/060071    International Application No.:    PCT/EP2008/065141
Publication Date: 14.05.2009 International Filing Date: 07.11.2008
IPC:
C07K 14/62 (2006.01), A61K 38/28 (2006.01)
Applicants: NOVO NORDISK A/S [DK/DK]; Novo Alle, DK-2880 Bagsværd (DK) (For All Designated States Except US).
GARIBAY, Patrick, William [US/DK]; (DK) (For US Only).
HØEG-JENSEN, Thomas [DK/DK]; (DK) (For US Only)
Inventors: GARIBAY, Patrick, William; (DK).
HØEG-JENSEN, Thomas; (DK)
Priority Data:
07120251.9 08.11.2007 EP
08161557.7 31.07.2008 EP
Title (EN) INSULIN DERIVATIVE
(FR) DÉRIVÉ DE L'INSULINE
Abstract: front page image
(EN)The present invention relates to novel human insulin derivatives which are soluble at physiological pH values and have a prolonged profile of action. The invention also relates to pharmaceutical compositions containing such derivatives and to methods of treating diabetes and hyperglycaemia using the insulin derivatives of the invention.
(FR)La présente invention porte sur de nouveaux dérivés de l'insuline humaine qui sont solubles à des valeurs de pH physiologiques et ont un profil d'action prolongé. L'invention porte également sur des compositions pharmaceutiques contenant de tels dérivés et sur des procédés de traitement du diabète et de l'hyperglycémie à l'aide des dérivés de l'insuline de l'invention.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)