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1. (WO2009059379) ANTIMICROBIAL COMPOSITIONS, FORMULATIONS AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/059379    International Application No.:    PCT/AU2008/001662
Publication Date: 14.05.2009 International Filing Date: 07.11.2008
IPC:
C07K 2/00 (2006.01), A61K 38/10 (2006.01), A61K 38/16 (2006.01)
Applicants: DYNAMIC MICROBIALS LIMITED [AU/AU]; Level 22 77 St Georges Terrace Perth, Western Australia 6000 (AU) (For All Designated States Except US).
WATT, Paul Michael [AU/AU]; (AU) (For US Only).
THOMAS, Wayne [AU/AU]; (AU) (For US Only).
HEINRICH, Tatjana Katharina [DE/AU]; (AU) (For US Only)
Inventors: WATT, Paul Michael; (AU).
THOMAS, Wayne; (AU).
HEINRICH, Tatjana Katharina; (AU)
Agent: OLIVE, Mark; c/- FB RICE & CO Level 23 44 Market Street Sydney, New South Wales 2000 (AU)
Priority Data:
60/986,179 07.11.2007 US
Title (EN) ANTIMICROBIAL COMPOSITIONS, FORMULATIONS AND USES THEREOF
(FR) COMPOSITIONS ET FORMULATIONS ANTIMICROBIENNES ET LEURS UTILISATIONS
Abstract: front page image
(EN)The present invention provides antimicrobial peptides and analogs thereof that are cytostatic or cytotoxic toward at least one gram-negative bacterium of the genus Acinetobacter including laboratory or clinical isolates of A.baumannii with low or non-detectable cytotoxicity against mammalian cells. Optionally, the antimicrobial peptides and analogs thereof are also cytotoxic or cytostatic against other unrelated bacteria such as Staphylococcus aureus.
(FR)La présente invention concerne des peptides antimicrobiens et des analogues de ceux-ci qui ont un effet cytostatique ou cytotoxique sur au moins une bactérie à Gram négatif du genre Acinetobacter, y compris des isolats de laboratoire ou cliniques d'A. baumannii ayant une cytotoxicité faible ou non détectable vis-à-vis des cellules de mammifères. Eventuellement, les peptides antimicrobiens et analogues de ceux-ci peuvent aussi avoir un effet cytostatique ou cytotoxique sur d'autres bactéries non apparentées telles que Staphylococcus aureus.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)