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1. (WO2009058968) BIOMARKER FOR ASSESSING RESPONSE TO FMS TREATMENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/058968    International Application No.:    PCT/US2008/081738
Publication Date: 07.05.2009 International Filing Date: 30.10.2008
IPC:
G01N 33/74 (2006.01), G01N 33/50 (2006.01)
Applicants: JANSSEN PHARMACEUTICA N.V. [BE/BE]; Turnhoutseweg 30 B-2340 Beerse (BE) (For All Designated States Except US).
MANTHEY, Carl, L. [US/US]; (US) (For US Only)
Inventors: MANTHEY, Carl, L.; (US)
Agent: JOHNSON, Philip S.; Johnson & Johnson One Johnson & Johnson Plaza New Brunswick, New Jersey 08933 (US)
Priority Data:
60/984,122 31.10.2007 US
Title (EN) BIOMARKER FOR ASSESSING RESPONSE TO FMS TREATMENT
(FR) BIOMARQUEUR UTILISÉ POUR ÉVALUER UNE RÉPONSE À UN TRAITEMENT DE FMS
Abstract: front page image
(EN)A biomarker that correlates to treatment with drugs that inhibit FMS is disclosed. This biomarker has been shown to have utility in assessing response to the compounds. The plasma level of the biomarker is increased upon treatment with FMS inhibitor compounds, thus indicating that this biomarker is involved in FMS activity.
(FR)L'invention porte sur un biomarqueur qui permet d'établir une corrélation avec un traitement au moyen de médicaments inhibant le FMS. L'utilité de ce biomarqueur dans l'évaluation d'une réponse aux composés a été prouvée. Un traitement avec des composés inhibiteurs de FMS augmente les niveaux de biomarqueur, ce qui indique que le biomarqueur est impliqué dans l'activité de FMS.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)