WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2009058769) PURIFICATION OF ANTIBODIES CONTAINING HYDROPHOBIC VARIANTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/058769    International Application No.:    PCT/US2008/081438
Publication Date: 07.05.2009 International Filing Date: 28.10.2008
IPC:
C07K 1/16 (2006.01), C07K 1/36 (2006.01), C07K 16/24 (2006.01)
Applicants: SCHERING CORPORATION [US/US]; 2000 Galloping Hill Road, Kenilworth, New Jersey 07033 (US) (For All Designated States Except US).
BLAISDELL, Steven, J. [US/US]; (US) (For US Only)
Inventors: BLAISDELL, Steven, J.; (US)
Agent: MOHAN-PETERSON, Sheela; Schering Corporation, Patent Dept. K-6-1 1990, 2000 Galloping Hill Road, Kenilworth, New Jersey 07033 (US)
Priority Data:
60/983,694 30.10.2007 US
Title (EN) PURIFICATION OF ANTIBODIES CONTAINING HYDROPHOBIC VARIANTS
(FR) PURIFICATION D'ANTICORPS CONTENANT DES VARIANTS HYDROPHOBES
Abstract: front page image
(EN)The present invention encompasses methods of purifying samples containing antibodies. In particular the present invention provides methods of reducing hydrophobic variants in these samples using a series of column chromatography steps, comprising protein A affinity chromatography, ion exchange chromatography and hydrophobic interaction chromatography.
(FR)L'invention concerne des procédés de purification d'échantillons contenant des anticorps. En particulier, la présente invention fournit des procédés pour réduire les variants hydrophobes dans ces échantillons à l'aide d'une série d'étapes de chromatographie sur colonne, comprenant une chromatographie d'affinité sur protéine A, une chromatographie par échange d'ions et une chromatographie hydrophobe.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)