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1. (WO2009058518) USE AND PRODUCTION OF NEUTRAL METALLPROTEASES IN A SERINE PROTEASE-FREE BACKGROUND
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/058518    International Application No.:    PCT/US2008/078942
Publication Date: 07.05.2009 International Filing Date: 06.10.2008
IPC:
C12N 9/54 (2006.01), C12N 15/75 (2006.01)
Applicants: DANISCO US INC. [US/US]; 925 Page Mill Road Palo Alto, California 94304 (US) (For All Designated States Except US).
LEE, Edwin [US/US]; (US) (For US Only).
SHAW, Andrew [US/US]; (US) (For US Only).
VAN KIMMENADE, Anita [NL/US]; (US) (For US Only).
WALLACE, Louise [ZA/US]; (US) (For US Only)
Inventors: LEE, Edwin; (US).
SHAW, Andrew; (US).
VAN KIMMENADE, Anita; (US).
WALLACE, Louise; (US)
Agent: KAMRIN T. MACKNIGHT; Danisco Us Inc., Genencor Division 925 Page Mill Road Palo Alto, California 94304 (US)
Priority Data:
60/984,040 31.10.2007 US
Title (EN) USE AND PRODUCTION OF NEUTRAL METALLPROTEASES IN A SERINE PROTEASE-FREE BACKGROUND
(FR) UTILISATION ET PRODUCTION DE MÉTALLOPROTÉASES NEUTRES DANS UN MILIEU EXEMPT DE SÉRINE PROTÉASE
Abstract: front page image
(EN)The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme in the relative absence of serine protease enzyme contaminants. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising Bacillus strains engineered to be deficient in multiple serine proteases, and their use in production of recombinant neutral metalloprotease(s).
(FR)La présente invention propose des procédés et des compositions comprenant au moins une enzyme de type métalloprotéase neutre en l'absence relative de contaminants enzymatiques de type sérine protéase. La métalloprotéase neutre peut être utilisée pour le nettoyage et dans d'autres applications. Dans un aspect particulièrement préféré, la présente invention propose des procédés et des compositions contenant des souches Bacillus génétiquement modifiées afin de supprimer la production des multiples sérines protéases, et leur utilisation pour produire une ou plusieurs métalloprotéase(s) neutre(s) recombinante(s).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)