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1. (WO2009058492) FC VARIANTS WITH ALTERED BINDING TO FCRN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/058492    International Application No.:    PCT/US2008/077250
Publication Date: 07.05.2009 International Filing Date: 22.09.2008
IPC:
C07K 16/28 (2006.01), C07K 16/32 (2006.01), C07K 16/22 (2006.01), C07K 16/08 (2006.01), A61K 39/395 (2006.01)
Applicants: XENCOR, INC [US/US]; 111 W. Lemon Ave. Monrovia, CA 91016 (US) (For All Designated States Except US).
CHAMBERLAIN, Aaron [US/US]; (US) (For US Only).
DAHIYAT, Bassil [US/US]; (US) (For US Only).
DESJARLAIS, John, Rudolph [US/US]; (US) (For US Only).
KARKI, Sher, Bahadur [NP/US]; (US) (For US Only)
Inventors: CHAMBERLAIN, Aaron; (US).
DAHIYAT, Bassil; (US).
DESJARLAIS, John, Rudolph; (US).
KARKI, Sher, Bahadur; (US)
Agent: MORGAN, LEWIS &BOCKIUS LLP; One Market Spear Street Tower San Francisco California 94105 (US)
Priority Data:
11/932,151 31.10.2007 US
Title (EN) FC VARIANTS WITH ALTERED BINDING TO FCRN
(FR) VARIANTES DE FC PRÉSENTANT UNE LIAISON MODIFIÉE À FCRN
Abstract: front page image
(EN)The present application relates to optimized IgG immunoglobulin variants, engineering methods for their generation, and their application, particularly for therapeutic purposes.
(FR)La présente invention concerne des variantes optimisées d'immunoglobuline IgG, des procédés d'ingénierie pour leur génération et leur application, notamment dans des buts thérapeutiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)