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1. (WO2009057139) NOVEL 4-(TETRAZOL-5-YL)-QUINAZOLINE DERIVATIVES AS ANTI CANCER AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/057139    International Application No.:    PCT/IN2008/000708
Publication Date: 07.05.2009 International Filing Date: 28.10.2008
IPC:
C07D 239/72 (2006.01), C07D 239/86 (2006.01), C07D 239/94 (2006.01), C07D 401/14 (2006.01), C07D 403/04 (2006.01), C07D 403/14 (2006.01), A61K 31/498 (2006.01), A61P 35/00 (2006.01)
Applicants: NATCO PHARMA LIMITED [IN/IN]; "Natco House", Road No.2 Banjara Hills Hyderabad Andhra Pradesh 500 033 (IN) (For All Designated States Except US).
KONAKANCHI, Durga Prasad [IN/IN]; (IN) (For US Only).
PULA, Subba Rao [IN/IN]; (IN) (For US Only).
ANANTHANENI, Lakshmi [IN/IN]; (IN) (For US Only).
PULLA REDDY, Muddasani [IN/IN]; (IN) (For US Only).
ADIBHATLA KALI SATYA, Bhujanga Rao [IN/IN]; (IN) (For US Only).
VENKAIAH CHOWDARY, Nannapaneni [IN/IN]; (IN) (For US Only)
Inventors: KONAKANCHI, Durga Prasad; (IN).
PULA, Subba Rao; (IN).
ANANTHANENI, Lakshmi; (IN).
PULLA REDDY, Muddasani; (IN).
ADIBHATLA KALI SATYA, Bhujanga Rao; (IN).
VENKAIAH CHOWDARY, Nannapaneni; (IN)
Priority Data:
2445/CHE/2007 29.10.2007 IN
Title (EN) NOVEL 4-(TETRAZOL-5-YL)-QUINAZOLINE DERIVATIVES AS ANTI CANCER AGENTS
(FR) NOUVEAUX DÉRIVÉS DE LA 4-(TÉTRAZOL-5-YL)-QUINAZOLINE EN TANT QU'AGENTS ANTI-CANCÉREUX
Abstract: front page image
(EN)The invention relates to substituted 4-(tetrazol-5-yl)-quinazoline derivatives of the formula-I, or pharmaceutically-acceptable salts thereof, which possess anti-proliferative activity such as anti-cancer activity and are accordingly useful in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of substituted 4-(tetrazol-5-yl)-quinazoline derivatives, to pharmaceutical compositions containing the compound and to its use in the manufacture of medicaments for the production of an anti-proliferative effect in a warm-blooded animal such as man.
(FR)L'invention concerne des dérivés substitués de 4-(tétrazol-5-yl)-quinazoline de la formule I, ou des sels acceptables du point de vue pharmaceutique de ceux-ci, qui possèdent une activité anti-proliférative telle qu'une activité anti-cancéreuse et qui s'utilisent, par conséquent, dans des procédés de traitement du corps humain ou animal. L'invention concerne également des procédés pour la fabrication de dérivés substitués de 4-(tétrazol-5-yl)-quinazoline, des compositions pharmaceutiques contenant le composé et son utilisation dans la fabrication de médicaments pour la production d'un effet anti-prolifératif dans un animal à sang chaud tel que l'homme.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)