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1. (WO2009056980) STABILIZED PEDIATRIC SUSPENSION OF CARISBAMATE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/056980    International Application No.:    PCT/IB2008/003331
Publication Date: 07.05.2009 International Filing Date: 31.10.2008
IPC:
A61K 9/00 (2006.01), A61K 31/27 (2006.01)
Applicants: JANSSEN PHARMACEUTICA, N.V. [BE/BE]; Turnhoutseweg 30, B-2340 Beerse (BE) (For All Designated States Except US).
EMBRECHTS, Roger [BE/BE]; (BE) (For US Only).
DE LEERSNIJDER, Cedric [BE/BE]; (BE) (For US Only)
Inventors: EMBRECHTS, Roger; (BE).
DE LEERSNIJDER, Cedric; (BE)
Agent: WARNER, James, Alexander; Carpmaels & Ransford, 43-45 Bloomsbury Square, London, WC1A 2RA (GB)
Priority Data:
60/984,144 31.10.2007 US
Title (EN) STABILIZED PEDIATRIC SUSPENSION OF CARISBAMATE
(FR) SUSPENSION PÉDIATRIQUE STABILISÉE DE CARISBAMATE
Abstract: front page image
(EN)The present invention provides a stabilized pharmaceutical suspension of carisbamate for pediatric and adult use. More particularly, the suspension is stabilized with hypromellose (HPMC) to prevent crystal growth of the suspended particles and to prevent re-crystallization of the drug product with change in polymorphic form.
(FR)La présente invention concerne une suspension pharmaceutique stabilisée de carisbamate destinée à être utilisée pour des enfants ou des adultes. Plus particulièrement, on stabilise ladite suspension avec de l'hypromellose (HPMC), en vue de prévenir la croissance cristalline des particules en suspension et la recristallisation du produit de médicament avec un changement de la forme polymorphe.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)