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Pub. No.:    WO/2009/056651    International Application No.:    PCT/EP2008/064894
Publication Date: 07.05.2009 International Filing Date: 03.11.2008
A61K 39/00 (2006.01), A61K 9/19 (2006.01), C07K 7/14 (2006.01), C07K 14/08 (2006.01), A61P 9/12 (2006.01)
Applicants: CYTOS BIOTECHNOLOGY AG [CH/CH]; Wagistrasse 25 CH-8952 Schlieren (CH) (For All Designated States Except US).
LANDOLT, Stefan [CH/CH]; (CH) (For US Only).
VOGT, Lorenz [CH/CH]; (CH) (For US Only).
ZUERCHER, Alexander [CH/CH]; (CH) (For US Only)
Inventors: LANDOLT, Stefan; (CH).
VOGT, Lorenz; (CH).
ZUERCHER, Alexander; (CH)
Agent: PETER, Stefan; Cytos Biotechnology AG IP & Legal Affairs Wagistrasse 25 CH-8952 Schlieren (CH)
Priority Data:
07119873.3 02.11.2007 EP
Abstract: front page image
(EN)The present invention is in the fields of medicine, vaccine and pharmaceutical formulation. The invention provides formulations comprising an angiotensin-virus-like particle conjugate and a stabilizer, wherein said stabilizer comprises a non-reducing disaccharide and a non-ionic surfactant. The lyophilized formulations are stable after a long time of storage at room temperature.
(FR)La présente invention appartient au domaine des médicaments, vaccins et des formulations pharmaceutiques. L'invention porte sur des formulations comprenant un conjugué angiotensine-particule de type virus et un stabilisant, ledit stabilisant comprenant un disaccharide non réducteur et un agent tensioactif non ionique. Les formulations lyophilisées sont stables après une longue période de stockage à température ambiante.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)