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Machine translation
1. (WO2009056617) 4,4-DISUBSTITUTED PIPERDINES AS RENIN INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/056617    International Application No.:    PCT/EP2008/064767
Publication Date: 07.05.2009 International Filing Date: 31.10.2008
IPC:
C07D 413/14 (2006.01), A61K 31/538 (2006.01)
Applicants: NOVARTIS AG [CH/CH]; Lichtstrasse 35 CH-4056 Basel (CH) (For All Designated States Except US).
HEROLD, Peter [CH/CH]; (CH) (For US Only).
MAH, Robert [CA/CH]; (CH) (For US Only).
TSCHINKE, Vincenzo [IT/CH]; (CH) (For US Only).
JELAKOVIC, Stjepan [HR/CH]; (CH) (For US Only).
STUTZ, Stefan [CH/CH]; (CH) (For US Only).
MARTI, Christiane [DE/CH]; (CH) (For US Only)
Inventors: HEROLD, Peter; (CH).
MAH, Robert; (CH).
TSCHINKE, Vincenzo; (CH).
JELAKOVIC, Stjepan; (CH).
STUTZ, Stefan; (CH).
MARTI, Christiane; (CH)
Priority Data:
07119884.0 02.11.2007 EP
Title (EN) 4,4-DISUBSTITUTED PIPERDINES AS RENIN INHIBITORS
(FR) PIPÉRIDINES 4,4-DISUBSTITUÉES
Abstract: front page image
(EN)The application relates to 4,4-disubstituted piperidinesof the general formula (I) and their salts, preferably their pharmaceutically acceptable salts, in which R2, has the meanings explained in the description, a process for their preparation and the use of these compounds as medicines, especially as renin inhibitors.
(FR)L'invention se rapporte : à des pipéridines 4,4-disubstituées de la formule générale (I) et à leurs sels, de préférence leurs sels pharmaceutiquement acceptables, où R2 est tel que défini dans la description; à un procédé de préparation de ces dernières; et à l'utilisation de ces composés comme médicaments, en particulier comme inhibiteurs de la rénine.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)