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1. (WO2009056555) CONTRAST AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/056555    International Application No.:    PCT/EP2008/064632
Publication Date: 07.05.2009 International Filing Date: 29.10.2008
A61K 49/04 (2006.01), C07C 237/46 (2006.01)
Applicants: GE HEALTHCARE AS [NO/NO]; P.O. Box 4220 Nydalen, Nycoveien 1-2, N-0401 Oslo (NO) (For All Designated States Except US).
WYNN, Duncan, George [GB/GB]; (GB) (For US Only).
NEWINGTON, Ian, Martin [GB/GB]; (GB) (For US Only).
WADSWORTH, Harry, John [GB/GB]; (GB) (For US Only)
Inventors: WYNN, Duncan, George; (GB).
NEWINGTON, Ian, Martin; (GB).
WADSWORTH, Harry, John; (GB)
Agent: HELGE, Tove, Aas; GE Healthcare AS, P.O. Box 4220 Nydalen, Nycoveien 1-2, N-0401 Oslo (NO)
Priority Data:
20075474 30.10.2007 NO
Abstract: front page image
(EN)The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds of the formula R-Y-X-Z-R where each R denotes a triiodinated phenyl residue further substituted by hydrophilic moieties, Y and Z are urea and urethane groups and X is a alkylene group which may be further substituted. The invention also relates to the use of such diagnostic compositions as contrast agents in diagnostic imaging and in particular in X-ray imaging, and to contrast media containing such compounds.
(FR)La présente invention concerne une classe de composés et des compositions diagnostiques contenant ces composés, lesdits composés étant des composés iodés de formule R-Y-X-Z-R où chaque R représente un résidu de phényle triiodé davantage substitué par des fractions hydrophiles, Y et Z sont des groupes urée et uréthane et X est un groupe alkylène qui peut encore être substitué. L'invention concerne également l'utilisation de telles compositions diagnostiques comme agents de contraste en imagerie diagnostique et en particulier en imagerie par rayons X, et des milieux de contraste contenant de tels composés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)