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1. WO2009054542 - DETECTION METHOD AND DETECTION APPARATUS

Publication Number WO/2009/054542
Publication Date 30.04.2009
International Application No. PCT/JP2008/069707
International Filing Date 23.10.2008
IPC
G01N 35/08 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
35Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/-G01N33/148; Handling materials therefor
08using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
G01N 21/05 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
01Arrangements or apparatus for facilitating the optical investigation
03Cuvette constructions
05Flow-through cuvettes
G01N 21/27 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
17Systems in which incident light is modified in accordance with the properties of the material investigated
25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
27using photo-electric detection
G01N 21/49 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
17Systems in which incident light is modified in accordance with the properties of the material investigated
47Scattering, i.e. diffuse reflection
49within a body or fluid
G01N 21/59 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
17Systems in which incident light is modified in accordance with the properties of the material investigated
59Transmissivity
G01N 37/00 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
37Details not covered by any other group of this subclass
CPC
G01N 2021/0346
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
01Arrangements or apparatus for facilitating the optical investigation
03Cuvette constructions
0346Capillary cells; Microcells
G01N 2035/00158
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
35Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
00029provided with flat sample substrates, e.g. slides
00099Characterised by type of test elements
00158Elements containing microarrays, i.e. "biochip"
G01N 21/0303
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
01Arrangements or apparatus for facilitating the optical investigation
03Cuvette constructions
0303Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment
G01N 21/05
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
01Arrangements or apparatus for facilitating the optical investigation
03Cuvette constructions
05Flow-through cuvettes
G01N 21/648
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
645Specially adapted constructive features of fluorimeters
648using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
Applicants
  • CANON KABUSHIKI KAISHA [JP]/[JP] (AllExceptUS)
  • IGATA, Eishi [JP]/[JP] (UsOnly)
Inventors
  • IGATA, Eishi
Agents
  • OKABE, Masao
Priority Data
2007-27955326.10.2007JP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DETECTION METHOD AND DETECTION APPARATUS
(FR) PROCÉDÉ DE DÉTECTION ET APPAREIL DE DÉTECTION
Abstract
(EN)
Provided is a method of adjusting detection sensitivity in detecting a sample in a channel. A detection method of optically detecting a sample includes: forming a multilayer flow, in which at least one of layers of the multilayer flow contains the sample; introducing light into at least one of layers of the multilayer flow; and detecting a signal generated from the multilayer flow in response to the introduced light, to detect the sample. The sample includes one of a chemical substance, a molecule, a cell, a particle, and a mixture thereof. At least one of fluids included in the multilayer flow has a refractive index different from a refractive index of another one of the fluids.
(FR)
L'invention concerne un procédé consistant à ajuster une sensibilité de détection lors de la détection d'un échantillon dans un canal. L'invention concerne également un procédé de détection consistant à détecter optiquement un échantillon, qui comprend les opérations consistant à : former un écoulement multicouche, dans lequel au moins l'une des couches de l'écoulement multicouche contient l'échantillon ; introduire de la lumière dans au moins l'une des couches de l'écoulement multicouche ; et détecter un signal généré à partir de l'écoulement multicouche en réponse à la lumière introduite, pour détecter l'échantillon. L'échantillon comprend l'un parmi une substance chimique, une molécule, une cellule, une particule et un mélange de celles-ci. Au moins l'un des fluides compris dans l'écoulement multicouche a un indice de réfraction différent d'un indice de réfraction d'un autre fluide parmi les fluides.
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