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Machine translation
1. (WO2009051671) IMPROVED METHODS OF PRODUCING RPE CELLS AND COMPOSITIONS OF RPE CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/051671    International Application No.:    PCT/US2008/011669
Publication Date: 23.04.2009 International Filing Date: 10.10.2008
IPC:
C12N 5/02 (2006.01), C12N 5/071 (2010.01)
Applicants: ADVANCED CELL TECHNOLOGY, INC. [US/US]; 381 Plantation Street Biotech V Worcester, MA 01605 (US) (For All Designated States Except US).
MALCUIT, Christopher [US/US]; (US) (For US Only).
LEMIEUX, Linda [US/US]; (US) (For US Only).
HOLMES, Willliam [US/US]; (US) (For US Only).
HUERTAS, Pedro [US/US]; (US) (For US Only).
VILNER, Lucy [US/US]; (US) (For US Only)
Inventors: MALCUIT, Christopher; (US).
LEMIEUX, Linda; (US).
HOLMES, Willliam; (US).
HUERTAS, Pedro; (US).
VILNER, Lucy; (US)
Agent: TESKIN, Robin, L.; Hunton & Williams 1900 K Street, N.W. Washington, D.C. 20006 (US)
Priority Data:
60/998,668 12.10.2007 US
60/998,766 12.10.2007 US
61/009,911 02.01.2008 US
61/009,908 02.01.2008 US
Title (EN) IMPROVED METHODS OF PRODUCING RPE CELLS AND COMPOSITIONS OF RPE CELLS
(FR) PROCÉDÉS AMÉLIORÉS POUR LA PRODUCTION DE CELLULES RPE ET DE COMPOSITIONS DE CELLULES RPE
Abstract: front page image
(EN)The present invention provides improved methods for producing RPE cells from human embryonic stem cells or from other human pluripotent stem cells. The invention also relates to human retinal pigmented epithelial cells derived from human embryonic stem cells or other human multipotent or pluripotent stem cells. hRPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The hRPE cells described herein are useful for treating retinal degenerative diseases.
(FR)La présente invention concerne des procédés améliorés pour la production de cellules RPE à partir de cellules souches d'embryon humain ou d'autres cellules souches pluripotentes humaines. L'invention a également pour objets des cellules épithéliales pigmentées de rétine humaine (hRPE) dérivées de cellules souches d'embryon humain ou d'autres cellules souches multipotentes ou pluripotentes humaines. Les cellules hRPE dérivées de cellules souches embryonnaires sont distinctes d'un point de vue moléculaire des cellules RPE dérivées d'adultes et de fœtus, et sont également distinctes des cellules souches embryonnaires. Les cellules hRPE décrites dans les présentes sont utiles au traitement de maladies dégénérescentes de la rétine.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)