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1. WO2009040562 - DUAL SPECIFICITY ANTIBODY FUSIONS

Publication Number WO/2009/040562
Publication Date 02.04.2009
International Application No. PCT/GB2008/003331
International Filing Date 26.09.2008
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
24
against cytokines, lymphokines or interferons
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
46
Hybrid immunoglobulins
C07K 16/00 (2006.01)
C07K 16/18 (2006.01)
C07K 16/24 (2006.01)
C07K 16/46 (2006.01)
CPC
C07K 16/00
C07K 16/18
C07K 16/245
C07K 16/468
C07K 2317/24
C07K 2317/31
Applicants
  • UCB PHARMA S.A. [BE/BE]; 60 Allée de la Recherche B-1070 Brussels, BE (AllExceptUS)
  • HUMPHREYS, David Paul [GB/GB]; GB (UsOnly)
  • DAVE, Emma [GB/GB]; GB (UsOnly)
Inventors
  • HUMPHREYS, David Paul; GB
  • DAVE, Emma; GB
Agents
  • THOMPSON, John; UCB Celltech 208 Bath Road Slough Berkshire SL1 3WE, GB
Priority Data
0718832.926.09.2007GB
0718834.526.09.2007GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DUAL SPECIFICITY ANTIBODY FUSIONS
(FR) FUSIONS D'ANTICORPS À DOUBLE SPÉCIFICITÉ
Abstract
(EN)
The present invention provides dual specificity antibody fusion proteins comprising an antibody Fab or Fab' fragment with specificity for an antigen of interest, said fragment being fused to at least one single domain antibody which has specificity for a second antigen of interest.
(FR)
La présente invention porte sur des protéines de fusion d'anticorps à double spécificité, comprenant un fragment Fab ou Fab' d'anticorps ayant une spécificité pour un antigène d'intérêt, ledit fragment étant fusionné à au moins un anticorps à domaine unique qui a une spécificité pour un second antigène d'intérêt.
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